Abstract
Tetracarbon organic acids are important platform chemicals that are widely used in the food, chemical, medicine, material industries and agriculture. Compared with the traditional petrochemical process, the production of tetracarbon organic acids by microbial fermentation is more promising due to milder reaction conditions, greener process and better environmental compatibility. This review summarizes the biosynthetic pathways and metabolic mechanisms for the production of tetracarbon organic acids, and illustrates recent advances, challenges, and future perspectives in the production of tetracarbon organic acids by naturally selected or purposefully engineered strains.
| Translated title of the contribution | Advances in the metabolic engineering for the production of tetracarbon organic acids |
|---|---|
| Original language | Chinese (Traditional) |
| Pages (from-to) | 1697-1720 |
| Number of pages | 24 |
| Journal | Shengwu Gongcheng Xuebao/Chinese Journal of Biotechnology |
| Volume | 37 |
| Issue number | 5 |
| DOIs | |
| State | Published - 25 May 2021 |