Concise total synthesis of aplysinellamides A and B

Haifeng Gan, Yu Huang, Weiyang Feng, Wentong Zhu, Kai Guo

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Concise and efficient total syntheses of bromotyrosine-derived metabolites aplysinellamides A and B, isolated from Australian marine sponge Aplysinella sp., have been accomplished in seven steps. A condensation between cinnamic acid and Boc-D-lysine methyl ester was applied to form the amide skeleton as a key step.

Original languageEnglish
Pages (from-to)336-339
Number of pages4
JournalJournal of Chemical Research
Volume39
Issue number6
DOIs
StatePublished - 1 Jun 2015

Keywords

  • Aplysinella species
  • Bromotyrosine
  • Marine sponge

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