Continuous Synthesis of Cyclohexene Oxide in a Micro-FlowSystem

Yu Zhou; Wei He; Zheng Fang; Kai Guo

doi:10.1002/slct.201803038

Continuous Synthesis of Cyclohexene Oxide in a Micro-FlowSystem

Yu Zhou, Wei He, Zheng Fang, Kai Guo

COLLEGE OF BIOTECHNOLOGY AND PHARMACEUTICAL ENGINEERING

Nanjing Tech University

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Epoxidation reaction catalyzed by dicyclohexylcarbodiimide(DCC) was realized in a microflow system, resulting in cyclohexene oxide with high yields. In this study, the epoxidation process of cyclohexene in MFS was investigated in detail. The optimal yield was obtained in such conditions: temperature 80°C, residence time 12 min, catalyst concentration 3%, ratio of cyclohexene to UHP 1:8. Basic additions played an important role in the collapse of adducts.

Original language	English
Pages (from-to)	13530-13533
Number of pages	4
Journal	ChemistrySelect
Volume	3
Issue number	47
DOIs	https://doi.org/10.1002/slct.201803038
State	Published - 19 Dec 2018

Keywords

DCC
cyclohexene oxide
micro-flow system

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10.1002/slct.201803038

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title = "Continuous Synthesis of Cyclohexene Oxide in a Micro-FlowSystem",

abstract = "Epoxidation reaction catalyzed by dicyclohexylcarbodiimide(DCC) was realized in a microflow system, resulting in cyclohexene oxide with high yields. In this study, the epoxidation process of cyclohexene in MFS was investigated in detail. The optimal yield was obtained in such conditions: temperature 80°C, residence time 12 min, catalyst concentration 3%, ratio of cyclohexene to UHP 1:8. Basic additions played an important role in the collapse of adducts.",

keywords = "DCC, cyclohexene oxide, micro-flow system",

author = "Yu Zhou and Wei He and Zheng Fang and Kai Guo",

note = "Publisher Copyright: {\textcopyright} 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim",

year = "2018",

month = dec,

day = "19",

doi = "10.1002/slct.201803038",

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AU - Zhou, Yu

AU - He, Wei

AU - Fang, Zheng

AU - Guo, Kai

PY - 2018/12/19

Y1 - 2018/12/19

N2 - Epoxidation reaction catalyzed by dicyclohexylcarbodiimide(DCC) was realized in a microflow system, resulting in cyclohexene oxide with high yields. In this study, the epoxidation process of cyclohexene in MFS was investigated in detail. The optimal yield was obtained in such conditions: temperature 80°C, residence time 12 min, catalyst concentration 3%, ratio of cyclohexene to UHP 1:8. Basic additions played an important role in the collapse of adducts.

AB - Epoxidation reaction catalyzed by dicyclohexylcarbodiimide(DCC) was realized in a microflow system, resulting in cyclohexene oxide with high yields. In this study, the epoxidation process of cyclohexene in MFS was investigated in detail. The optimal yield was obtained in such conditions: temperature 80°C, residence time 12 min, catalyst concentration 3%, ratio of cyclohexene to UHP 1:8. Basic additions played an important role in the collapse of adducts.

KW - DCC

KW - cyclohexene oxide

KW - micro-flow system

UR - http://www.scopus.com/inward/record.url?scp=85058804496&partnerID=8YFLogxK

U2 - 10.1002/slct.201803038

DO - 10.1002/slct.201803038

M3 - 文章

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SN - 2365-6549

VL - 3

SP - 13530

EP - 13533

JO - ChemistrySelect

JF - ChemistrySelect

IS - 47

ER -

Continuous Synthesis of Cyclohexene Oxide in a Micro-FlowSystem

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Keywords

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