Abstract
A highly efficient copper-catalyzed α-amination of aliphatic aldehydes for the synthesis of α-amino acetals using secondary amines with readily removable protecting groups as a nitrogen source was developed. This reaction can be operated under very mild conditions, affording the desired products in moderate to good yields.
| Original language | English |
|---|---|
| Pages (from-to) | 5458-5460 |
| Number of pages | 3 |
| Journal | Chemical Communications |
| Volume | 47 |
| Issue number | 19 |
| DOIs | |
| State | Published - 26 Apr 2011 |
| Externally published | Yes |