Pyridinium-Substituted TetraphenylethyleneEntailing Alkyne Moiety: Enhancement of Photosensitizing Efficiency and Antimicrobial Activity

Xue You, Huili Ma, Yuancheng Wang, Guanxin Zhang, Qian Peng, Libing Liu, Shu Wang, Deqing Zhang

Research output: Contribution to journalArticlepeer-review

39 Scopus citations

Abstract

Apart from sensing and imaging, luminogens with aggregation-induced emission (AIE) are also interesting for photosensitizing. The photosensitizing behavior and bacteria-killing performance of a pyridinium-substituted tetraphenylethylene with an alkyne group (TPE-A-Py+) is reported herein. Interestingly, TPE-A-Py+ exhibits higher photosensitizing efficiency than TPE-Py+ (without alkyne group) when I was used as a counteranion. This is well explained by the fact that the ΔΕST between the excited singlet state (S1) and triplet state (T1) was lower for TPE-A-Py+ than for TPE-Py+, according to theoretical calculations. Moreover, replacement of I with other anions (PF6 , N(SO2CF3)2 and BPh4 ) led to a decrease of photosensitizing efficiency for TPE-A-Py+. Notably, TPE-A-Py+ could be used as an efficient photosensitizer to photo-inactivate ampicillin-resistant (ampr) E. coli at low concentration under white-light irradiation very quickly.

Original languageEnglish
Pages (from-to)1013-1019
Number of pages7
JournalChemistry - An Asian Journal
Volume12
Issue number9
DOIs
StatePublished - 4 May 2017
Externally publishedYes

Keywords

  • aggregation-induced emission
  • fluorescent probes
  • photodynamic therapy
  • singlet oxygen
  • tetraphenylethylene

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