Synthesis of Alkyl Indium Reagents by Using Unactivated Alkyl Chlorides and Their Applications in Palladium-Catalyzed Cross-Coupling Reactions with Aryl Halides

Bing Zhi Chen, Man Ling Zhi, Chuang Xin Wang, Xue Qiang Chu, Zhi Liang Shen, Teck Peng Loh

Research output: Contribution to journalArticlepeer-review

39 Scopus citations

Abstract

An efficient method for the preparation of alkyl indium reagents by using unactivated and cheap alkyl chlorides as substrates in the presence of indium and LiI was developed. The thus-formed alkyl indium species effectively underwent palladium-catalyzed cross-coupling reactions with aryl halides with wide functional group tolerance.

Original languageEnglish
Pages (from-to)1902-1905
Number of pages4
JournalOrganic Letters
Volume20
Issue number7
DOIs
StatePublished - 6 Apr 2018

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