Synthetic studies toward anisatin: A formal synthesis of (±)-8-deoxyanisatin

Teck Peng Loh; Qi Ying Hu

doi:10.1021/ol006918c

Synthetic studies toward anisatin: A formal synthesis of (±)-8-deoxyanisatin

Teck Peng Loh, Qi Ying Hu

National University of Singapore

Research output: Contribution to journal › Article › peer-review

41 Scopus citations

Abstract

equations presented An efficient strategy to construct the congested C-7a quaternary chiral center of anisatin was developed, by way of an Eschenmoser-Claisen rearrangement. Conversion of the resultant amide to Kende's ε-lactone intermediate 3 in four steps completed a concise formal synthesis of (±)-8-deoxyanisatin (2).

Original language	English
Pages (from-to)	279-281
Number of pages	3
Journal	Organic Letters
Volume	3
Issue number	2
DOIs	https://doi.org/10.1021/ol006918c
State	Published - 25 Jan 2001
Externally published	Yes

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@article{d9d9585482be49588bf74b7ba14b5644,

title = "Synthetic studies toward anisatin: A formal synthesis of (±)-8-deoxyanisatin",

abstract = "equations presented An efficient strategy to construct the congested C-7a quaternary chiral center of anisatin was developed, by way of an Eschenmoser-Claisen rearrangement. Conversion of the resultant amide to Kende's ε-lactone intermediate 3 in four steps completed a concise formal synthesis of (±)-8-deoxyanisatin (2).",

author = "Loh, {Teck Peng} and Hu, {Qi Ying}",

year = "2001",

month = jan,

day = "25",

doi = "10.1021/ol006918c",

language = "英语",

volume = "3",

pages = "279--281",

journal = "Organic Letters",

issn = "1523-7060",

publisher = "American Chemical Society",

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T1 - Synthetic studies toward anisatin

T2 - A formal synthesis of (±)-8-deoxyanisatin

AU - Loh, Teck Peng

AU - Hu, Qi Ying

PY - 2001/1/25

Y1 - 2001/1/25

N2 - equations presented An efficient strategy to construct the congested C-7a quaternary chiral center of anisatin was developed, by way of an Eschenmoser-Claisen rearrangement. Conversion of the resultant amide to Kende's ε-lactone intermediate 3 in four steps completed a concise formal synthesis of (±)-8-deoxyanisatin (2).

AB - equations presented An efficient strategy to construct the congested C-7a quaternary chiral center of anisatin was developed, by way of an Eschenmoser-Claisen rearrangement. Conversion of the resultant amide to Kende's ε-lactone intermediate 3 in four steps completed a concise formal synthesis of (±)-8-deoxyanisatin (2).

UR - http://www.scopus.com/inward/record.url?scp=0035945796&partnerID=8YFLogxK

U2 - 10.1021/ol006918c

DO - 10.1021/ol006918c

M3 - 文章

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AN - SCOPUS:0035945796

SN - 1523-7060

VL - 3

SP - 279

EP - 281

JO - Organic Letters

JF - Organic Letters

IS - 2

ER -

Synthetic studies toward anisatin: A formal synthesis of (±)-8-deoxyanisatin

Abstract

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