TY - JOUR
T1 - 医用组织粘合剂的研究进展
AU - Zhu, Haofang
AU - Mao, Hongli
AU - Gu, Zhongwei
N1 - Publisher Copyright:
© 2020, The Editorial Board of Materials China. All right reserved.
PY - 2020/8/1
Y1 - 2020/8/1
N2 - Medical tissue adhesives have gained wide attention because of their obvious advantages over conventional sutures such as easy operation, non-invasive sealing, and immediate hemostasis. At present, a variety of commercial medical tissue adhesives based on various materials have been developed to replace or assist sutures in the application of repair and regeneration of heart, blood vessels, lungs and other soft tissues. However, existing tissue adhesives are usually either cytotoxic, fragile, or lacking adhesive strength. Therefore, significant research endeavors have been focused on developing a safe and effective tissue adhesive to overcome these problems. In this review, we firstly introduce the basic research status and adhesion mechanism of various types of tissue adhesives. Then the current hotspots and recent progress of medical tissue adhesives, as well as their clinical translation applications are summarized in detail. Finally, the future research direction and the prospect of tissue adhesives are proposed.
AB - Medical tissue adhesives have gained wide attention because of their obvious advantages over conventional sutures such as easy operation, non-invasive sealing, and immediate hemostasis. At present, a variety of commercial medical tissue adhesives based on various materials have been developed to replace or assist sutures in the application of repair and regeneration of heart, blood vessels, lungs and other soft tissues. However, existing tissue adhesives are usually either cytotoxic, fragile, or lacking adhesive strength. Therefore, significant research endeavors have been focused on developing a safe and effective tissue adhesive to overcome these problems. In this review, we firstly introduce the basic research status and adhesion mechanism of various types of tissue adhesives. Then the current hotspots and recent progress of medical tissue adhesives, as well as their clinical translation applications are summarized in detail. Finally, the future research direction and the prospect of tissue adhesives are proposed.
KW - Clinical translation
KW - Commercial tissue adhesive
KW - Research progress
KW - Soft tissue adhesive
UR - http://www.scopus.com/inward/record.url?scp=85092019230&partnerID=8YFLogxK
U2 - 10.7502/j.issn.1674-3962.202006028
DO - 10.7502/j.issn.1674-3962.202006028
M3 - 文献综述
AN - SCOPUS:85092019230
SN - 1674-3962
VL - 39
SP - 535
EP - 550
JO - Materials China
JF - Materials China
IS - 7-8
ER -