A click-activated fluorescent probe for selective detection of hydrazoic acid and its application in biological imaging

Yi Zhou; Yue Wei Yao; Qi Qi; Yuan Fang; Jing Yun Li; Cheng Yao

doi:10.1039/c3cc40698a

A click-activated fluorescent probe for selective detection of hydrazoic acid and its application in biological imaging

Yi Zhou, Yue Wei Yao, Qi Qi, Yuan Fang, Jing Yun Li, Cheng Yao

School of Chemistry and Moleculai Engineering

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

Here we present a new approach to aqueous hydrazoic acid detection through the synthesis and evaluation of an alkyne-based fluorescent probe, which could be applied in the monitoring of hydrazoic acid in both living Hela cells and larval zebrafish. This probe can also serve as an early warning automaton which would alert when both azide and protons exist over the threshold value.

Original language	English
Pages (from-to)	5924-5926
Number of pages	3
Journal	Chemical Communications
Volume	49
Issue number	53
DOIs	https://doi.org/10.1039/c3cc40698a
State	Published - 6 Jun 2013

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abstract = "Here we present a new approach to aqueous hydrazoic acid detection through the synthesis and evaluation of an alkyne-based fluorescent probe, which could be applied in the monitoring of hydrazoic acid in both living Hela cells and larval zebrafish. This probe can also serve as an early warning automaton which would alert when both azide and protons exist over the threshold value.",

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AU - Zhou, Yi

AU - Yao, Yue Wei

AU - Qi, Qi

AU - Fang, Yuan

AU - Li, Jing Yun

AU - Yao, Cheng

PY - 2013/6/6

Y1 - 2013/6/6

N2 - Here we present a new approach to aqueous hydrazoic acid detection through the synthesis and evaluation of an alkyne-based fluorescent probe, which could be applied in the monitoring of hydrazoic acid in both living Hela cells and larval zebrafish. This probe can also serve as an early warning automaton which would alert when both azide and protons exist over the threshold value.

AB - Here we present a new approach to aqueous hydrazoic acid detection through the synthesis and evaluation of an alkyne-based fluorescent probe, which could be applied in the monitoring of hydrazoic acid in both living Hela cells and larval zebrafish. This probe can also serve as an early warning automaton which would alert when both azide and protons exist over the threshold value.

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M3 - 文章

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SP - 5924

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JO - Chemical Communications

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A click-activated fluorescent probe for selective detection of hydrazoic acid and its application in biological imaging

Abstract

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