A convenient synthesis of 5-arylidenethiazolidine-2,4-diones catalyzed by alkaline ionic liquid

Yi Hu; Tao Xie; Kai Mei Fu; Hui Kang; Ping Wei; He Huang

doi:10.3987/COM-08-11533

A convenient synthesis of 5-arylidenethiazolidine-2,4-diones catalyzed by alkaline ionic liquid

Yi Hu, Tao Xie, Kai Mei Fu, Hui Kang, Ping Wei, He Huang

Nanjing Tech University

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

A series of 5-arylidenethiazolidine-2,4-diones was synthesized by the Knoevenagel condensation of thiazolidine-2,4-dione with aromatic aldehydes with alkaline ionic liquid l-butyl-3-mefhylimidazolium hydroxide ([bmim]OH) as dual solvent and catalyst. This method provides many advantages such as being environmentally benign, simple work-up, short reaction times, obtaining in good to excellent yields, and the reusability of ionic liquid.

Original language	English
Pages (from-to)	757-761
Number of pages	5
Journal	Heterocycles
Volume	78
Issue number	3
DOIs	https://doi.org/10.3987/COM-08-11533
State	Published - 1 Mar 2009

Keywords

5-Arylidenethiazolidine-2,4-dione
Aromatic Aldehyde
Condensation
Lonic Liquid
Thiazolidine-2,4-dione

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10.3987/COM-08-11533

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abstract = "A series of 5-arylidenethiazolidine-2,4-diones was synthesized by the Knoevenagel condensation of thiazolidine-2,4-dione with aromatic aldehydes with alkaline ionic liquid l-butyl-3-mefhylimidazolium hydroxide ([bmim]OH) as dual solvent and catalyst. This method provides many advantages such as being environmentally benign, simple work-up, short reaction times, obtaining in good to excellent yields, and the reusability of ionic liquid.",

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AU - Hu, Yi

AU - Xie, Tao

AU - Fu, Kai Mei

AU - Kang, Hui

AU - Wei, Ping

AU - Huang, He

PY - 2009/3/1

Y1 - 2009/3/1

N2 - A series of 5-arylidenethiazolidine-2,4-diones was synthesized by the Knoevenagel condensation of thiazolidine-2,4-dione with aromatic aldehydes with alkaline ionic liquid l-butyl-3-mefhylimidazolium hydroxide ([bmim]OH) as dual solvent and catalyst. This method provides many advantages such as being environmentally benign, simple work-up, short reaction times, obtaining in good to excellent yields, and the reusability of ionic liquid.

AB - A series of 5-arylidenethiazolidine-2,4-diones was synthesized by the Knoevenagel condensation of thiazolidine-2,4-dione with aromatic aldehydes with alkaline ionic liquid l-butyl-3-mefhylimidazolium hydroxide ([bmim]OH) as dual solvent and catalyst. This method provides many advantages such as being environmentally benign, simple work-up, short reaction times, obtaining in good to excellent yields, and the reusability of ionic liquid.

KW - 5-Arylidenethiazolidine-2,4-dione

KW - Aromatic Aldehyde

KW - Condensation

KW - Lonic Liquid

KW - Thiazolidine-2,4-dione

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JO - Heterocycles

JF - Heterocycles

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ER -

A convenient synthesis of 5-arylidenethiazolidine-2,4-diones catalyzed by alkaline ionic liquid

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Keywords

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