A facile approach to 2-alkoxyindolin-3-one and its application to the synthesis of: N -benzyl matemone

Makoto Shimizu; Hayao Imazato; Isao Mizota; Yusong Zhu

doi:10.1039/c9ra02204j

A facile approach to 2-alkoxyindolin-3-one and its application to the synthesis of: N -benzyl matemone

Makoto Shimizu, Hayao Imazato, Isao Mizota, Yusong Zhu

School of energy science and engineering

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

2-Alkoxycarbonylindolin-3-one is synthesized from a methoxyglycine derivative via a 1,2-aza-Brook rearrangement followed by cyclization with bis(trimethylsilyl)aluminum chloride. A short-step synthesis of N-benzyl matemone is successfully carried out using the present indolin-3-one synthesis.

Original language	English
Pages (from-to)	17341-17346
Number of pages	6
Journal	RSC Advances
Volume	9
Issue number	30
DOIs	https://doi.org/10.1039/c9ra02204j
State	Published - 2019

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abstract = "2-Alkoxycarbonylindolin-3-one is synthesized from a methoxyglycine derivative via a 1,2-aza-Brook rearrangement followed by cyclization with bis(trimethylsilyl)aluminum chloride. A short-step synthesis of N-benzyl matemone is successfully carried out using the present indolin-3-one synthesis.",

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AU - Mizota, Isao

AU - Zhu, Yusong

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AB - 2-Alkoxycarbonylindolin-3-one is synthesized from a methoxyglycine derivative via a 1,2-aza-Brook rearrangement followed by cyclization with bis(trimethylsilyl)aluminum chloride. A short-step synthesis of N-benzyl matemone is successfully carried out using the present indolin-3-one synthesis.

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JO - RSC Advances

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A facile approach to 2-alkoxyindolin-3-one and its application to the synthesis of: N -benzyl matemone

Abstract

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