A flavone-based ESIPT fluorescent sensor for detection of N2H4 in aqueous solution and gas state and its imaging in living cells

Xiaodong Jin, Caozhi Liu, Xuemei Wang, Hai Huang, Xueqiong Zhang, Hongjun Zhu

Research output: Contribution to journalArticlepeer-review

84 Scopus citations

Abstract

A novel probe (1) based on flavone was synthesized and used for the detection of hydrazine in a mixture of phosphate buffer saline (PBS, pH 7.0, 20 mM) and DMSO (1/9, vPBS/vDMSO) at room temperature. The limit of detection is 0.15 μM (4.8 ppb), which is lower than the U.S. Environmental Protection Agency standard (10 ppb). Notably, probe 1 could be used for gas state discrimination of hydrazine with different concentrations through color changes from readily prepared strips. Additionally, probe 1 could also be applied for the imaging of hydrazine in living cells.

Original languageEnglish
Pages (from-to)141-149
Number of pages9
JournalSensors and Actuators B: Chemical
Volume216
DOIs
StatePublished - 1 Sep 2015

Keywords

  • Biological imaging
  • ESIPT
  • Flavone
  • Gas detection
  • Hydrazine

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