A novel method for stereoselective synthesis of β-trifluoromethylated homoallylic alcohols in water

Teck Peng Loh, Xu Ran Li

Research output: Contribution to journalArticlepeer-review

47 Scopus citations

Abstract

The indium-mediated allylation reaction of aldehydes with 1,1,1 -trifluor and bromo-2-butene in water afforded an important trifluoromethylated building black β-trifluoromethylated homoallylic alcohol with high yield and excellent diastereoselectivity.

Original languageEnglish
Pages (from-to)869-872
Number of pages4
JournalTetrahedron Letters
Volume38
Issue number5
DOIs
StatePublished - 3 Feb 1997
Externally publishedYes

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