Abstract
A quinoline-based fluorescent chemosensor was reported for the simultaneous detection of Zn2+ and Cd2+ in aqueous solution. In HEPES buffer, among various metal ions, only Zn2+ and Cd2+ exhibited fluorescence enhancement at 497 nm accompanied by the red-shift emission wavelength. The mechanism was proposed that internal charge transfer effect induced by binding with Zn2+ or Cd2+ produced the fluorescence changes. With the addition of cysteine, the fluorescent solution containing sensor and Cd2+ show the decreased fluorescence at 497 nm and the increased fluorescence at 420 nm, which was attributed to the dissociation of the complex formed by sensor and Cd2+. In contrast, the fluorescence of solution containing sensor and Zn2+ is unchanged with the addition of Cys. Furthermore, the confocal microscopy experiments indicated that this sensor can provide real-time detection for intracellular Zn2+ and Cd2+.
Original language | English |
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Pages (from-to) | 1116-1122 |
Number of pages | 7 |
Journal | Sensors and Actuators B: Chemical |
Volume | 188 |
DOIs | |
State | Published - 2013 |
Keywords
- Biological imaging
- Cysteine
- Fluorescent sensor
- Quinoline-based derivative
- Zn/Cd ions