A reusable microRNA sensor based on the electrocatalytic property of heteroduplexlated copper nanoclusters

Zhaoyin Wang; Ling Si; Jianchun Bao; Zhihui Dai

doi:10.1039/c5cc01081k

A reusable microRNA sensor based on the electrocatalytic property of heteroduplexlated copper nanoclusters

Zhaoyin Wang, Ling Si, Jianchun Bao, Zhihui Dai

Nanjing Normal University

Research output: Contribution to journal › Article › peer-review

33 Scopus citations

Abstract

DNA-RNA heteroduplexes have been used as templates for copper nanocluster (CuNC) formation for the first time. Taking advantage of the electrocatalysis of CuNCs, quantitation of miRNA can thus be accomplished. More importantly, by simply operating several rounds of CuNC formation, repeated detection of miRNA has further been realized, which is rare in miRNA biosensors.

Original language	English
Pages (from-to)	6305-6307
Number of pages	3
Journal	Chemical Communications
Volume	51
Issue number	29
DOIs	https://doi.org/10.1039/c5cc01081k
State	Published - 14 Apr 2015
Externally published	Yes

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10.1039/c5cc01081k

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title = "A reusable microRNA sensor based on the electrocatalytic property of heteroduplexlated copper nanoclusters",

abstract = "DNA-RNA heteroduplexes have been used as templates for copper nanocluster (CuNC) formation for the first time. Taking advantage of the electrocatalysis of CuNCs, quantitation of miRNA can thus be accomplished. More importantly, by simply operating several rounds of CuNC formation, repeated detection of miRNA has further been realized, which is rare in miRNA biosensors.",

author = "Zhaoyin Wang and Ling Si and Jianchun Bao and Zhihui Dai",

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AU - Wang, Zhaoyin

AU - Si, Ling

AU - Bao, Jianchun

AU - Dai, Zhihui

N1 - Publisher Copyright: © The Royal Society of Chemistry 2015.

PY - 2015/4/14

Y1 - 2015/4/14

N2 - DNA-RNA heteroduplexes have been used as templates for copper nanocluster (CuNC) formation for the first time. Taking advantage of the electrocatalysis of CuNCs, quantitation of miRNA can thus be accomplished. More importantly, by simply operating several rounds of CuNC formation, repeated detection of miRNA has further been realized, which is rare in miRNA biosensors.

AB - DNA-RNA heteroduplexes have been used as templates for copper nanocluster (CuNC) formation for the first time. Taking advantage of the electrocatalysis of CuNCs, quantitation of miRNA can thus be accomplished. More importantly, by simply operating several rounds of CuNC formation, repeated detection of miRNA has further been realized, which is rare in miRNA biosensors.

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DO - 10.1039/c5cc01081k

M3 - 文章

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AN - SCOPUS:84925943109

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A reusable microRNA sensor based on the electrocatalytic property of heteroduplexlated copper nanoclusters

Abstract

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