A Review of Recent Advances in Microneedle-Based Sensing within the Dermal ISF That Could Transform Medical Testing

Jun Li; Meng Wei; Bingbing Gao

doi:10.1021/acssensors.4c00142

A Review of Recent Advances in Microneedle-Based Sensing within the Dermal ISF That Could Transform Medical Testing

Jun Li, Meng Wei, Bingbing Gao

School of Pharmaceutical Sciences

Nanjing Tech University

Research output: Contribution to journal › Review article › peer-review

16 Scopus citations

Abstract

Interstitial fluid (ISF) has attracted extensive attention in an extremely wide range of areas due to its unique advantages, such as portability, high precision, comfortable operation, and superior stability. In recent years, the microneedle (MN) technique has been considered to be an excellent tool for extracting ISF because it is painless and noninvasive. Recent reports have shown that MN has good application prospects in ISF extraction. In this review, we provide comprehensive and in-depth insight into integrated MN devices for ISF detection, covering the basic structure as well as the fabrication of integrated MN devices and various applications in ISF extraction. Challenges and prospects are highlighted, with a discussion on how to transition such MN-integrated devices toward personalized healthcare monitoring systems.

Original language	English
Pages (from-to)	1149-1161
Number of pages	13
Journal	ACS Sensors
Volume	9
Issue number	3
DOIs	https://doi.org/10.1021/acssensors.4c00142
State	Published - 22 Mar 2024

Keywords

Interstitial fluid
biosensor
materials
microelectronics
microfluidics
microneedles
real-time monitoring
structures

Access to Document

10.1021/acssensors.4c00142

Cite this

@article{28beff57eba94cc3a60537e5e09e16e6,

title = "A Review of Recent Advances in Microneedle-Based Sensing within the Dermal ISF That Could Transform Medical Testing",

abstract = "Interstitial fluid (ISF) has attracted extensive attention in an extremely wide range of areas due to its unique advantages, such as portability, high precision, comfortable operation, and superior stability. In recent years, the microneedle (MN) technique has been considered to be an excellent tool for extracting ISF because it is painless and noninvasive. Recent reports have shown that MN has good application prospects in ISF extraction. In this review, we provide comprehensive and in-depth insight into integrated MN devices for ISF detection, covering the basic structure as well as the fabrication of integrated MN devices and various applications in ISF extraction. Challenges and prospects are highlighted, with a discussion on how to transition such MN-integrated devices toward personalized healthcare monitoring systems.",

keywords = "Interstitial fluid, biosensor, materials, microelectronics, microfluidics, microneedles, real-time monitoring, structures",

author = "Jun Li and Meng Wei and Bingbing Gao",

note = "Publisher Copyright: {\textcopyright} 2024 American Chemical Society.",

year = "2024",

month = mar,

day = "22",

doi = "10.1021/acssensors.4c00142",

language = "英语",

volume = "9",

pages = "1149--1161",

journal = "ACS Sensors",

issn = "2379-3694",

publisher = "American Chemical Society",

number = "3",

}

TY - JOUR

T1 - A Review of Recent Advances in Microneedle-Based Sensing within the Dermal ISF That Could Transform Medical Testing

AU - Li, Jun

AU - Wei, Meng

AU - Gao, Bingbing

PY - 2024/3/22

Y1 - 2024/3/22

N2 - Interstitial fluid (ISF) has attracted extensive attention in an extremely wide range of areas due to its unique advantages, such as portability, high precision, comfortable operation, and superior stability. In recent years, the microneedle (MN) technique has been considered to be an excellent tool for extracting ISF because it is painless and noninvasive. Recent reports have shown that MN has good application prospects in ISF extraction. In this review, we provide comprehensive and in-depth insight into integrated MN devices for ISF detection, covering the basic structure as well as the fabrication of integrated MN devices and various applications in ISF extraction. Challenges and prospects are highlighted, with a discussion on how to transition such MN-integrated devices toward personalized healthcare monitoring systems.

AB - Interstitial fluid (ISF) has attracted extensive attention in an extremely wide range of areas due to its unique advantages, such as portability, high precision, comfortable operation, and superior stability. In recent years, the microneedle (MN) technique has been considered to be an excellent tool for extracting ISF because it is painless and noninvasive. Recent reports have shown that MN has good application prospects in ISF extraction. In this review, we provide comprehensive and in-depth insight into integrated MN devices for ISF detection, covering the basic structure as well as the fabrication of integrated MN devices and various applications in ISF extraction. Challenges and prospects are highlighted, with a discussion on how to transition such MN-integrated devices toward personalized healthcare monitoring systems.

KW - Interstitial fluid

KW - biosensor

KW - materials

KW - microelectronics

KW - microfluidics

KW - microneedles

KW - real-time monitoring

KW - structures

UR - http://www.scopus.com/inward/record.url?scp=85187685865&partnerID=8YFLogxK

U2 - 10.1021/acssensors.4c00142

DO - 10.1021/acssensors.4c00142

M3 - 文献综述

C2 - 38478049

AN - SCOPUS:85187685865

SN - 2379-3694

VL - 9

SP - 1149

EP - 1161

JO - ACS Sensors

JF - ACS Sensors

IS - 3

ER -

A Review of Recent Advances in Microneedle-Based Sensing within the Dermal ISF That Could Transform Medical Testing

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this