A simple and efficient one-pot synthesis of spirooxindoles in water under microwave irradiation conditions

Song Lei Zhu; Shun Jun Ji; Kai Zhao; Yong Zhang

doi:10.2174/157017808784049489

A simple and efficient one-pot synthesis of spirooxindoles in water under microwave irradiation conditions

Song Lei Zhu, Shun Jun Ji, Kai Zhao, Yong Zhang

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

A simple and efficient method for the synthesis of spirooxindoles derivatives by one-pot reactions of isatins, activated methylene reagents and activated carbonyl compounds in water under microwave irradiation was reported. This protocol has the advantages of short reaction time, high yields, easy work-up procedure and environmentally benign characters.

Original language	English
Pages (from-to)	319-323
Number of pages	5
Journal	Letters in Organic Chemistry
Volume	5
Issue number	4
DOIs	https://doi.org/10.2174/157017808784049489
State	Published - 2008
Externally published	Yes

Keywords

Aqueous media
Microwave irradiation
Spircoxindoles
Three-component synthesis

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title = "A simple and efficient one-pot synthesis of spirooxindoles in water under microwave irradiation conditions",

abstract = "A simple and efficient method for the synthesis of spirooxindoles derivatives by one-pot reactions of isatins, activated methylene reagents and activated carbonyl compounds in water under microwave irradiation was reported. This protocol has the advantages of short reaction time, high yields, easy work-up procedure and environmentally benign characters.",

keywords = "Aqueous media, Microwave irradiation, Spircoxindoles, Three-component synthesis",

author = "Zhu, {Song Lei} and Ji, {Shun Jun} and Kai Zhao and Yong Zhang",

year = "2008",

doi = "10.2174/157017808784049489",

language = "英语",

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AU - Zhu, Song Lei

AU - Ji, Shun Jun

AU - Zhao, Kai

AU - Zhang, Yong

PY - 2008

Y1 - 2008

N2 - A simple and efficient method for the synthesis of spirooxindoles derivatives by one-pot reactions of isatins, activated methylene reagents and activated carbonyl compounds in water under microwave irradiation was reported. This protocol has the advantages of short reaction time, high yields, easy work-up procedure and environmentally benign characters.

AB - A simple and efficient method for the synthesis of spirooxindoles derivatives by one-pot reactions of isatins, activated methylene reagents and activated carbonyl compounds in water under microwave irradiation was reported. This protocol has the advantages of short reaction time, high yields, easy work-up procedure and environmentally benign characters.

KW - Aqueous media

KW - Microwave irradiation

KW - Spircoxindoles

KW - Three-component synthesis

UR - http://www.scopus.com/inward/record.url?scp=50249118608&partnerID=8YFLogxK

U2 - 10.2174/157017808784049489

DO - 10.2174/157017808784049489

M3 - 文章

AN - SCOPUS:50249118608

SN - 1570-1786

VL - 5

SP - 319

EP - 323

JO - Letters in Organic Chemistry

JF - Letters in Organic Chemistry

IS - 4

ER -

A simple and efficient one-pot synthesis of spirooxindoles in water under microwave irradiation conditions

Abstract

Keywords

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