A simple and practical synthesis of α-trifluoromethylated alcohols in water

Teck Peng Loh, Xu Ran Li

Research output: Contribution to journalArticlepeer-review

37 Scopus citations

Abstract

A simple and practical preparation of α-trifluoromethylated alcohols in water via indium-mediated allylation reaction and tin-mediated indium trichloride-promoted allylation reaction of trifluoroacetaldehyde hydrate and its ethyl hemiacetal is described in this paper.

Original languageEnglish
Pages (from-to)5611-5622
Number of pages12
JournalTetrahedron
Volume55
Issue number17
DOIs
StatePublished - 23 Apr 1999
Externally publishedYes

Keywords

  • Allylation
  • Indium
  • Water
  • α-Trifluoromethylated alcohols

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