A thiophen-thiooxorhodamine conjugate fluorescent probe for detecting mercury in aqueous media and living cells

Yi Zhou; Xue Yan You; Yuan Fang; Ju Ying Li; Ke Liu; Cheng Yao

doi:10.1039/c0ob00452a

A thiophen-thiooxorhodamine conjugate fluorescent probe for detecting mercury in aqueous media and living cells

Yi Zhou, Xue Yan You, Yuan Fang, Ju Ying Li, Ke Liu, Cheng Yao

School of Chemistry and Moleculai Engineering

Nanjing Tech University

Research output: Contribution to journal › Article › peer-review

88 Scopus citations

Abstract

A rhodamine-based sensor RB-S2 was designed and synthesized by combination of the thiospirolacton chromophore and the thiophen ring block with high affinity to Hg²⁺. Probe RB-S2 exhibits high selectivity and excellent sensitivity in both absorbance and fluorescence detection of Hg²⁺ in aqueous solution. In addition, fluorescent imaging of Hg²⁺ in MCF-7 cells is also successfully demonstrated.

Original language	English
Pages (from-to)	4819-4822
Number of pages	4
Journal	Organic and Biomolecular Chemistry
Volume	8
Issue number	21
DOIs	https://doi.org/10.1039/c0ob00452a
State	Published - 7 Nov 2010

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abstract = "A rhodamine-based sensor RB-S2 was designed and synthesized by combination of the thiospirolacton chromophore and the thiophen ring block with high affinity to Hg2+. Probe RB-S2 exhibits high selectivity and excellent sensitivity in both absorbance and fluorescence detection of Hg2+ in aqueous solution. In addition, fluorescent imaging of Hg2+ in MCF-7 cells is also successfully demonstrated.",

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AU - Zhou, Yi

AU - You, Xue Yan

AU - Fang, Yuan

AU - Li, Ju Ying

AU - Liu, Ke

AU - Yao, Cheng

PY - 2010/11/7

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AB - A rhodamine-based sensor RB-S2 was designed and synthesized by combination of the thiospirolacton chromophore and the thiophen ring block with high affinity to Hg2+. Probe RB-S2 exhibits high selectivity and excellent sensitivity in both absorbance and fluorescence detection of Hg2+ in aqueous solution. In addition, fluorescent imaging of Hg2+ in MCF-7 cells is also successfully demonstrated.

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M3 - 文章

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AN - SCOPUS:77957914072

SN - 1477-0520

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ER -

A thiophen-thiooxorhodamine conjugate fluorescent probe for detecting mercury in aqueous media and living cells

Abstract

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