Amine salt-catalyzed synthesis of 5-substituted 1H-tetrazoles from nitriles

Yi Zhou; Cheng Yao; Renjie Ni; Gaowen Yang

doi:10.1080/00397910903318583

Amine salt-catalyzed synthesis of 5-substituted 1H-tetrazoles from nitriles

Yi Zhou, Cheng Yao, Renjie Ni, Gaowen Yang

School of Chemistry and Moleculai Engineering

Research output: Contribution to journal › Article › peer-review

33 Scopus citations

Abstract

The [3+2] cycloaddition reaction between sodium azide and various organic nitriles proceeds smoothly in the presence of amine salts as catalyst in dimethylformamide. The corresponding 5-substituted 1-H tetrazoles were obtained under mild condition in good to excellent yields. Supplemental materials are available for this article. Go to the publisher's online edition of Synthetic Communications ®to view the free supplemental file.

Original language	English
Pages (from-to)	2624-2632
Number of pages	9
Journal	Synthetic Communications
Volume	40
Issue number	17
DOIs	https://doi.org/10.1080/00397910903318583
State	Published - 2010

Keywords

Amine salt catalyst
[3+2] cycloaddition
azide
heterocycles
tetrazole

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10.1080/00397910903318583

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abstract = "The [3+2] cycloaddition reaction between sodium azide and various organic nitriles proceeds smoothly in the presence of amine salts as catalyst in dimethylformamide. The corresponding 5-substituted 1-H tetrazoles were obtained under mild condition in good to excellent yields. Supplemental materials are available for this article. Go to the publisher's online edition of Synthetic Communications {\textregistered}to view the free supplemental file.",

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AU - Zhou, Yi

AU - Yao, Cheng

AU - Ni, Renjie

AU - Yang, Gaowen

PY - 2010

Y1 - 2010

N2 - The [3+2] cycloaddition reaction between sodium azide and various organic nitriles proceeds smoothly in the presence of amine salts as catalyst in dimethylformamide. The corresponding 5-substituted 1-H tetrazoles were obtained under mild condition in good to excellent yields. Supplemental materials are available for this article. Go to the publisher's online edition of Synthetic Communications ®to view the free supplemental file.

AB - The [3+2] cycloaddition reaction between sodium azide and various organic nitriles proceeds smoothly in the presence of amine salts as catalyst in dimethylformamide. The corresponding 5-substituted 1-H tetrazoles were obtained under mild condition in good to excellent yields. Supplemental materials are available for this article. Go to the publisher's online edition of Synthetic Communications ®to view the free supplemental file.

KW - Amine salt catalyst

KW - [3+2] cycloaddition

KW - azide

KW - heterocycles

KW - tetrazole

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M3 - 文章

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ER -

Amine salt-catalyzed synthesis of 5-substituted 1H-tetrazoles from nitriles

Abstract

Keywords

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