Aqueous C-H aminomethylation of phenols by iodine catalysis

Zhi Hua Zhou, Ben Wang, Yao Ding, Teck Peng Loh, Jie Sheng Tian

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

A transition-metal-free strategy regarding an iodine-sodium percarbonate catalysis to achieve the ortho-aminomethylation of phenols in aqueous media has been developed. This method can effectively broaden a wide range of phenols, tolerate sensitive functional groups, and achieve the late-stage functionalization of ten functional molecules that contain phenolic structures.

Original languageEnglish
Pages (from-to)223-226
Number of pages4
JournalChemical Communications
Volume59
Issue number2
DOIs
StatePublished - 30 Nov 2022

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