Asymmetric functionalization of gold nanoparticles with oligonucleotides

Xiaoyang Xu; Nathaniel L. Rosi; Yuhuang Wang; Fengwei Huo; Chad A. Mirkin

doi:10.1021/ja061980b

Asymmetric functionalization of gold nanoparticles with oligonucleotides

Xiaoyang Xu, Nathaniel L. Rosi, Yuhuang Wang, Fengwei Huo, Chad A. Mirkin

Northwestern University

Research output: Contribution to journal › Article › peer-review

336 Scopus citations

Abstract

Gold nanoparticles (AuNPs) were anisotropically functionalized with two different oligonucleotide sequences using magnetic microparticles as geometric restriction templates for site-selective enzymatic extension of particle-bound oligonucleotides. The divalent linking capability of the resulting AuNPs allowed for the design and programmable assembly of discrete nanoparticle heterostructures.

Original language	English
Pages (from-to)	9286-9287
Number of pages	2
Journal	Journal of the American Chemical Society
Volume	128
Issue number	29
DOIs	https://doi.org/10.1021/ja061980b
State	Published - 26 Jul 2006
Externally published	Yes

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10.1021/ja061980b

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title = "Asymmetric functionalization of gold nanoparticles with oligonucleotides",

abstract = "Gold nanoparticles (AuNPs) were anisotropically functionalized with two different oligonucleotide sequences using magnetic microparticles as geometric restriction templates for site-selective enzymatic extension of particle-bound oligonucleotides. The divalent linking capability of the resulting AuNPs allowed for the design and programmable assembly of discrete nanoparticle heterostructures.",

author = "Xiaoyang Xu and Rosi, {Nathaniel L.} and Yuhuang Wang and Fengwei Huo and Mirkin, {Chad A.}",

year = "2006",

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AU - Xu, Xiaoyang

AU - Rosi, Nathaniel L.

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AU - Huo, Fengwei

AU - Mirkin, Chad A.

PY - 2006/7/26

Y1 - 2006/7/26

N2 - Gold nanoparticles (AuNPs) were anisotropically functionalized with two different oligonucleotide sequences using magnetic microparticles as geometric restriction templates for site-selective enzymatic extension of particle-bound oligonucleotides. The divalent linking capability of the resulting AuNPs allowed for the design and programmable assembly of discrete nanoparticle heterostructures.

AB - Gold nanoparticles (AuNPs) were anisotropically functionalized with two different oligonucleotide sequences using magnetic microparticles as geometric restriction templates for site-selective enzymatic extension of particle-bound oligonucleotides. The divalent linking capability of the resulting AuNPs allowed for the design and programmable assembly of discrete nanoparticle heterostructures.

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U2 - 10.1021/ja061980b

DO - 10.1021/ja061980b

M3 - 文章

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AN - SCOPUS:33746373975

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VL - 128

SP - 9286

EP - 9287

JO - Journal of the American Chemical Society

JF - Journal of the American Chemical Society

IS - 29

ER -

Asymmetric functionalization of gold nanoparticles with oligonucleotides

Abstract

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