BF3-promoted reactions of α-amino acetals with alkynes to 2,5-disubstituted pyrroles

Zhi Yuan Gao; Yu He; Lan Yang Li; Jie Sheng Tian; Teck Peng Loh

doi:10.1039/d2qo00405d

BF₃-promoted reactions of α-amino acetals with alkynes to 2,5-disubstituted pyrroles

Zhi Yuan Gao, Yu He, Lan Yang Li, Jie Sheng Tian, Teck Peng Loh

School of Chemistry and Moleculai Engineering

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

An efficient BF₃-promoted cyclization of α-amino acetals with alkynes for the assembly of substituted pyrroles has been developed. This cascade process uses easily accessible α-amino acetals as raw materials and can be achieved under mild conditions through a simple metal-free operation.

Original language	English
Pages (from-to)	3317-3321
Number of pages	5
Journal	Organic Chemistry Frontiers
Volume	9
Issue number	12
DOIs	https://doi.org/10.1039/d2qo00405d
State	Published - 12 May 2022

Access to Document

10.1039/d2qo00405d

Cite this

@article{8cfddb686bb24a868c815f48b6c4f5a0,

title = "BF3-promoted reactions of α-amino acetals with alkynes to 2,5-disubstituted pyrroles",

abstract = "An efficient BF3-promoted cyclization of α-amino acetals with alkynes for the assembly of substituted pyrroles has been developed. This cascade process uses easily accessible α-amino acetals as raw materials and can be achieved under mild conditions through a simple metal-free operation.",

author = "Gao, {Zhi Yuan} and Yu He and Li, {Lan Yang} and Tian, {Jie Sheng} and Loh, {Teck Peng}",

note = "Publisher Copyright: {\textcopyright} 2022 The Royal Society of Chemistry",

year = "2022",

month = may,

day = "12",

doi = "10.1039/d2qo00405d",

language = "英语",

volume = "9",

pages = "3317--3321",

journal = "Organic Chemistry Frontiers",

issn = "2052-4110",

publisher = "Royal Society of Chemistry",

number = "12",

}

TY - JOUR

T1 - BF3-promoted reactions of α-amino acetals with alkynes to 2,5-disubstituted pyrroles

AU - Gao, Zhi Yuan

AU - He, Yu

AU - Li, Lan Yang

AU - Tian, Jie Sheng

AU - Loh, Teck Peng

PY - 2022/5/12

Y1 - 2022/5/12

N2 - An efficient BF3-promoted cyclization of α-amino acetals with alkynes for the assembly of substituted pyrroles has been developed. This cascade process uses easily accessible α-amino acetals as raw materials and can be achieved under mild conditions through a simple metal-free operation.

AB - An efficient BF3-promoted cyclization of α-amino acetals with alkynes for the assembly of substituted pyrroles has been developed. This cascade process uses easily accessible α-amino acetals as raw materials and can be achieved under mild conditions through a simple metal-free operation.

UR - http://www.scopus.com/inward/record.url?scp=85133618180&partnerID=8YFLogxK

U2 - 10.1039/d2qo00405d

DO - 10.1039/d2qo00405d

M3 - 文章

AN - SCOPUS:85133618180

SN - 2052-4110

VL - 9

SP - 3317

EP - 3321

JO - Organic Chemistry Frontiers

JF - Organic Chemistry Frontiers

IS - 12

ER -

BF₃-promoted reactions of α-amino acetals with alkynes to 2,5-disubstituted pyrroles

Abstract

Access to Document

Other files and links

Fingerprint

Cite this