TY - JOUR
T1 - Biotechnological applications of Yarrowia lipolytica
T2 - Past, present and future
AU - Liu, Hu Hu
AU - Ji, Xiao Jun
AU - Huang, He
N1 - Publisher Copyright:
© 2015 Elsevier Inc.
PY - 2015
Y1 - 2015
N2 - Non-conventional yeasts have attracted increasing interest due to their biochemical characteristics and potential applications. Yarrowia lipolytica is a non-conventional yeast with specific characteristics and physiology. The potential physiological and metabolic capabilities of Y. lipolytica, which can assimilate many different carbon sources, including typical hydrophilic and hydrophobic materials, are reviewed in this paper. Concerning the uptake and metabolism substrates, this review focuses particularly on low-cost raw materials, such as glycerol. Moreover, this review presents the results of safety studies of Y. lipolytica. Finally, the wide applications of Y. lipolytica, such as functional enzyme production, metabolite synthesis and environmental bioremediation, are reviewed in this paper. Recently, with the development of system biology and synthetic biology, it was concluded that these technologies will provide new opportunities for potential applications of Y. lipolytica in the future.
AB - Non-conventional yeasts have attracted increasing interest due to their biochemical characteristics and potential applications. Yarrowia lipolytica is a non-conventional yeast with specific characteristics and physiology. The potential physiological and metabolic capabilities of Y. lipolytica, which can assimilate many different carbon sources, including typical hydrophilic and hydrophobic materials, are reviewed in this paper. Concerning the uptake and metabolism substrates, this review focuses particularly on low-cost raw materials, such as glycerol. Moreover, this review presents the results of safety studies of Y. lipolytica. Finally, the wide applications of Y. lipolytica, such as functional enzyme production, metabolite synthesis and environmental bioremediation, are reviewed in this paper. Recently, with the development of system biology and synthetic biology, it was concluded that these technologies will provide new opportunities for potential applications of Y. lipolytica in the future.
KW - Applications
KW - Characteristics
KW - Metabolism
KW - Physiology
KW - Yarrowia lipolytica
UR - http://www.scopus.com/inward/record.url?scp=84939156334&partnerID=8YFLogxK
U2 - 10.1016/j.biotechadv.2015.07.010
DO - 10.1016/j.biotechadv.2015.07.010
M3 - 文献综述
C2 - 26248319
AN - SCOPUS:84939156334
SN - 0734-9750
VL - 33
SP - 1522
EP - 1546
JO - Biotechnology Advances
JF - Biotechnology Advances
IS - 8
ER -