Concise total synthesis of 1,3-diphenylpropane derivatives griffithanes A, B and F

Haifeng Gan, Weiwei Cao, Weiyang Feng, Kai Guo

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Concise and efficient total syntheses of diarylpropanes griffithane A, B and F, isolated from Combretum griffithii, have been accomplished from methoxybenzaldehyde. The Claisen-Schmidt condensation between aldehyde and acetophenone was applied to form chalcone as a key step. The structures of chalcones are confirmed by crystal X-ray crystallography.

Original languageEnglish
Pages (from-to)416-420
Number of pages5
JournalJournal of Chemical Research
Volume39
Issue number7
DOIs
StatePublished - 1 Jul 2015

Keywords

  • Chalcone
  • Combretum griffithii
  • Diarylpropane
  • Total synthesis

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