Continuous flow synthesis of coumarin

An Bang Chen, Xin Li, Yang Zhi Zhou, Ling Ling Huang, Zheng Fang, Hai Feng Gan, Kai Guo

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

2 Scopus citations

Abstract

Flow chemistry, as a rapidly emerging technology, is exploited to provide a safe and scalable route for the pharmaceutically interesting coumarin. Here, a continuous flow approach for the generation of coumarin is reported, which relies on the two connected coil reactors design. The synthesis of coumarin has been performed successfully in high conversion on small scale and can be scaled up substantially.

Original languageEnglish
Title of host publicationAdvances in Chemical Engineering III
Pages936-941
Number of pages6
DOIs
StatePublished - 2013
Event3rd International Conference on Chemical Engineering and Advanced Materials, CEAM 2013 - Guangzhou, China
Duration: 6 Jul 20137 Jul 2013

Publication series

NameAdvanced Materials Research
Volume781-784
ISSN (Print)1022-6680

Conference

Conference3rd International Conference on Chemical Engineering and Advanced Materials, CEAM 2013
Country/TerritoryChina
CityGuangzhou
Period6/07/137/07/13

Keywords

  • Continuous flow approach
  • Coumarin
  • Flow chemistry

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