Copper(II)-catalyzed preparation of alkylindium compounds and applications in cross-coupling reactions both in aqueous media

Peng Wang; Bing Zhi Chen; Yi Cong Guo; Weidong Rao; Zhi Liang Shen

doi:10.1016/j.tetlet.2019.151288

Copper(II)-catalyzed preparation of alkylindium compounds and applications in cross-coupling reactions both in aqueous media

Peng Wang, Bing Zhi Chen, Yi Cong Guo, Weidong Rao, Zhi Liang Shen

School of Chemistry and Moleculai Engineering

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

An efficient water-based method for the synthesis of alkylindium compound in the presence of a catalytic amount of cheap and readily available CuSO₄·5H₂O (10 mol%) was developed. The thus-generated alkylindium compounds effectively underwent palladium-catalyzed cross-coupling reactions with a myriad of aryl halides in aqueous media, leading to the cross-coupled products in modest to high yields. The mildness of the formed alkyl organometallics allowed the tolerance to various important functional groups incorporated in both substrates of alkyl iodides and aryl halides.

Original language	English
Article number	151288
Journal	Tetrahedron Letters
Volume	60
Issue number	49
DOIs	https://doi.org/10.1016/j.tetlet.2019.151288
State	Published - 5 Dec 2019

Keywords

Alkylindium compound
Copper catalysis
Indium
Water

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10.1016/j.tetlet.2019.151288

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title = "Copper(II)-catalyzed preparation of alkylindium compounds and applications in cross-coupling reactions both in aqueous media",

abstract = "An efficient water-based method for the synthesis of alkylindium compound in the presence of a catalytic amount of cheap and readily available CuSO4·5H2O (10 mol%) was developed. The thus-generated alkylindium compounds effectively underwent palladium-catalyzed cross-coupling reactions with a myriad of aryl halides in aqueous media, leading to the cross-coupled products in modest to high yields. The mildness of the formed alkyl organometallics allowed the tolerance to various important functional groups incorporated in both substrates of alkyl iodides and aryl halides.",

keywords = "Alkylindium compound, Copper catalysis, Indium, Water",

author = "Peng Wang and Chen, {Bing Zhi} and Guo, {Yi Cong} and Weidong Rao and Shen, {Zhi Liang}",

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T1 - Copper(II)-catalyzed preparation of alkylindium compounds and applications in cross-coupling reactions both in aqueous media

AU - Wang, Peng

AU - Chen, Bing Zhi

AU - Guo, Yi Cong

AU - Rao, Weidong

AU - Shen, Zhi Liang

PY - 2019/12/5

Y1 - 2019/12/5

N2 - An efficient water-based method for the synthesis of alkylindium compound in the presence of a catalytic amount of cheap and readily available CuSO4·5H2O (10 mol%) was developed. The thus-generated alkylindium compounds effectively underwent palladium-catalyzed cross-coupling reactions with a myriad of aryl halides in aqueous media, leading to the cross-coupled products in modest to high yields. The mildness of the formed alkyl organometallics allowed the tolerance to various important functional groups incorporated in both substrates of alkyl iodides and aryl halides.

AB - An efficient water-based method for the synthesis of alkylindium compound in the presence of a catalytic amount of cheap and readily available CuSO4·5H2O (10 mol%) was developed. The thus-generated alkylindium compounds effectively underwent palladium-catalyzed cross-coupling reactions with a myriad of aryl halides in aqueous media, leading to the cross-coupled products in modest to high yields. The mildness of the formed alkyl organometallics allowed the tolerance to various important functional groups incorporated in both substrates of alkyl iodides and aryl halides.

KW - Alkylindium compound

KW - Copper catalysis

KW - Indium

KW - Water

UR - http://www.scopus.com/inward/record.url?scp=85074383996&partnerID=8YFLogxK

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DO - 10.1016/j.tetlet.2019.151288

M3 - 文章

AN - SCOPUS:85074383996

SN - 0040-4039

VL - 60

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 49

M1 - 151288

ER -

Copper(II)-catalyzed preparation of alkylindium compounds and applications in cross-coupling reactions both in aqueous media

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Keywords

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