Cyanine-modified near-infrared upconversion nanoprobe for ratiometric sensing of N2H4 in living cells

Chuan Jian Li; Min An Ye; Pei Pei Su; Cheng Yao; Yi Zhou

doi:10.1016/j.saa.2020.119153

Cyanine-modified near-infrared upconversion nanoprobe for ratiometric sensing of N₂H₄ in living cells

Chuan Jian Li, Min An Ye, Pei Pei Su, Cheng Yao, Yi Zhou

School of Chemistry and Moleculai Engineering

Nanjing Tech University

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Although being as an important chemical material in industry, hydrazine (N₂H₄) is highly toxic to the humans and animals. The development of sensitive methods for the detection of hydrazine is meaningful. Herein, we develop a new organic-inorganic hybrid nanoprobe for the detection of N₂H₄ based on luminescent resonance energy transfer (LRET) process. The nanoprobe contains N₂H₄-responsive NIR cyanine dye (CQM1) and α-cyclodextrin (CD) anchored on the surface of lanthanide-doped upconversion nanophosphors (UCNPs). In the presence of hydrazine, the hybrid materials (CQM1-UCNPs) showed the a large ratiometric luminescent signal change with high sensitivity and selectivity. More importantly, by taking advantage of ratiometric Upconversion luminescent (UCL) signal and the features of NIR emission/excitation, the nanoprobe was successfully applied for visualization of hydrazine in living cells for the first time.

Original language	English
Article number	119153
Journal	Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy
Volume	247
DOIs	https://doi.org/10.1016/j.saa.2020.119153
State	Published - 15 Feb 2021

Keywords

Hydrazine
NIR-excited imaging
Ratiometric
Upconversion nanoprobe

Access to Document

10.1016/j.saa.2020.119153

Cite this

@article{cfc7ed754f094f8caeaf2a64c483c18a,

title = "Cyanine-modified near-infrared upconversion nanoprobe for ratiometric sensing of N2H4 in living cells",

abstract = "Although being as an important chemical material in industry, hydrazine (N2H4) is highly toxic to the humans and animals. The development of sensitive methods for the detection of hydrazine is meaningful. Herein, we develop a new organic-inorganic hybrid nanoprobe for the detection of N2H4 based on luminescent resonance energy transfer (LRET) process. The nanoprobe contains N2H4-responsive NIR cyanine dye (CQM1) and α-cyclodextrin (CD) anchored on the surface of lanthanide-doped upconversion nanophosphors (UCNPs). In the presence of hydrazine, the hybrid materials (CQM1-UCNPs) showed the a large ratiometric luminescent signal change with high sensitivity and selectivity. More importantly, by taking advantage of ratiometric Upconversion luminescent (UCL) signal and the features of NIR emission/excitation, the nanoprobe was successfully applied for visualization of hydrazine in living cells for the first time.",

keywords = "Hydrazine, NIR-excited imaging, Ratiometric, Upconversion nanoprobe",

author = "Li, {Chuan Jian} and Ye, {Min An} and Su, {Pei Pei} and Cheng Yao and Yi Zhou",

note = "Publisher Copyright: {\textcopyright} 2020 Elsevier B.V.",

year = "2021",

month = feb,

day = "15",

doi = "10.1016/j.saa.2020.119153",

language = "英语",

volume = "247",

journal = "Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy",

issn = "1386-1425",

publisher = "Elsevier B.V.",

}

TY - JOUR

T1 - Cyanine-modified near-infrared upconversion nanoprobe for ratiometric sensing of N2H4 in living cells

AU - Li, Chuan Jian

AU - Ye, Min An

AU - Su, Pei Pei

AU - Yao, Cheng

AU - Zhou, Yi

PY - 2021/2/15

Y1 - 2021/2/15

N2 - Although being as an important chemical material in industry, hydrazine (N2H4) is highly toxic to the humans and animals. The development of sensitive methods for the detection of hydrazine is meaningful. Herein, we develop a new organic-inorganic hybrid nanoprobe for the detection of N2H4 based on luminescent resonance energy transfer (LRET) process. The nanoprobe contains N2H4-responsive NIR cyanine dye (CQM1) and α-cyclodextrin (CD) anchored on the surface of lanthanide-doped upconversion nanophosphors (UCNPs). In the presence of hydrazine, the hybrid materials (CQM1-UCNPs) showed the a large ratiometric luminescent signal change with high sensitivity and selectivity. More importantly, by taking advantage of ratiometric Upconversion luminescent (UCL) signal and the features of NIR emission/excitation, the nanoprobe was successfully applied for visualization of hydrazine in living cells for the first time.

AB - Although being as an important chemical material in industry, hydrazine (N2H4) is highly toxic to the humans and animals. The development of sensitive methods for the detection of hydrazine is meaningful. Herein, we develop a new organic-inorganic hybrid nanoprobe for the detection of N2H4 based on luminescent resonance energy transfer (LRET) process. The nanoprobe contains N2H4-responsive NIR cyanine dye (CQM1) and α-cyclodextrin (CD) anchored on the surface of lanthanide-doped upconversion nanophosphors (UCNPs). In the presence of hydrazine, the hybrid materials (CQM1-UCNPs) showed the a large ratiometric luminescent signal change with high sensitivity and selectivity. More importantly, by taking advantage of ratiometric Upconversion luminescent (UCL) signal and the features of NIR emission/excitation, the nanoprobe was successfully applied for visualization of hydrazine in living cells for the first time.

KW - Hydrazine

KW - NIR-excited imaging

KW - Ratiometric

KW - Upconversion nanoprobe

UR - http://www.scopus.com/inward/record.url?scp=85095916374&partnerID=8YFLogxK

U2 - 10.1016/j.saa.2020.119153

DO - 10.1016/j.saa.2020.119153

M3 - 文章

C2 - 33188975

AN - SCOPUS:85095916374

SN - 1386-1425

VL - 247

JO - Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy

JF - Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy

M1 - 119153

ER -

Cyanine-modified near-infrared upconversion nanoprobe for ratiometric sensing of N₂H₄ in living cells

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this