Dehydrogenative etherification homocoupling of heterocyclic N-oxides

Dong Zhang, Kai Qiao, Xin Yuan, Mingwei Zheng, Zheng Fang, Li Wan, Kai Guo

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

A novel approach was developed for the dehydrogenative etherification homocoupling of heterocyclic N-oxides in the presence of silver oxide and PyBroP. Various substrates were well tolerated and the desired products were obtained in moderate to good yields. Generally, this reaction features excellent functional group compatibility, broad substrate scope and good regioselectivity.

Original languageEnglish
Pages (from-to)1752-1756
Number of pages5
JournalTetrahedron Letters
Volume59
Issue number18
DOIs
StatePublished - 2 May 2018

Keywords

  • Homocoupling
  • O-tethered
  • PyBroP
  • Quinoline
  • Regioselective

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