Design, synthesis and application in biological imaging of a novel red fluorescent dye based on a rhodanine derivative

Zijing Li; Bin Huang; Yuan Wang; Wenbo Yuan; Yijing Wu; Ruitao Yu; Guichuan Xing; Taotao Zou; Youtian Tao

doi:10.1039/d0ra08998b

Design, synthesis and application in biological imaging of a novel red fluorescent dye based on a rhodanine derivative

Zijing Li, Bin Huang, Yuan Wang, Wenbo Yuan, Yijing Wu, Ruitao Yu, Guichuan Xing, Taotao Zou, Youtian Tao

SCHOOL OF FLEXIBLE ELECTRONICS(FUTURE TECHNOLOGIES)|INSTITUTE OF ADVANCED MATERIALS(IAM)

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

A novel acceptor-donor-acceptor type molecule, namely 2-triphenylamine-1,3-dia[2-(3-ethyl-4-oxo-thiazolidin-2-ylidene)-malononitrile] (2RDNTPA), is designed and synthesized. 2RDNTPA exhibits a large Stokes shift of 244 nm and red fluorescence emission of 629 nm with a decent photoluminescence quantum yield of 13%. Furthermore, as a potential red fluorescent dye, 2RDNTPA can be applied in fluorescence imaging of living cancer cells (HepG2) with negligible cytotoxicity and a half maximal inhibitory concentration much more than 100 μM.

Original language	English
Pages (from-to)	160-163
Number of pages	4
Journal	RSC Advances
Volume	11
Issue number	1
DOIs	https://doi.org/10.1039/d0ra08998b
State	Published - 10 Dec 2020

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abstract = "A novel acceptor-donor-acceptor type molecule, namely 2-triphenylamine-1,3-dia[2-(3-ethyl-4-oxo-thiazolidin-2-ylidene)-malononitrile] (2RDNTPA), is designed and synthesized. 2RDNTPA exhibits a large Stokes shift of 244 nm and red fluorescence emission of 629 nm with a decent photoluminescence quantum yield of 13%. Furthermore, as a potential red fluorescent dye, 2RDNTPA can be applied in fluorescence imaging of living cancer cells (HepG2) with negligible cytotoxicity and a half maximal inhibitory concentration much more than 100 μM.",

author = "Zijing Li and Bin Huang and Yuan Wang and Wenbo Yuan and Yijing Wu and Ruitao Yu and Guichuan Xing and Taotao Zou and Youtian Tao",

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T1 - Design, synthesis and application in biological imaging of a novel red fluorescent dye based on a rhodanine derivative

AU - Li, Zijing

AU - Huang, Bin

AU - Wang, Yuan

AU - Yuan, Wenbo

AU - Wu, Yijing

AU - Yu, Ruitao

AU - Xing, Guichuan

AU - Zou, Taotao

AU - Tao, Youtian

PY - 2020/12/10

Y1 - 2020/12/10

N2 - A novel acceptor-donor-acceptor type molecule, namely 2-triphenylamine-1,3-dia[2-(3-ethyl-4-oxo-thiazolidin-2-ylidene)-malononitrile] (2RDNTPA), is designed and synthesized. 2RDNTPA exhibits a large Stokes shift of 244 nm and red fluorescence emission of 629 nm with a decent photoluminescence quantum yield of 13%. Furthermore, as a potential red fluorescent dye, 2RDNTPA can be applied in fluorescence imaging of living cancer cells (HepG2) with negligible cytotoxicity and a half maximal inhibitory concentration much more than 100 μM.

AB - A novel acceptor-donor-acceptor type molecule, namely 2-triphenylamine-1,3-dia[2-(3-ethyl-4-oxo-thiazolidin-2-ylidene)-malononitrile] (2RDNTPA), is designed and synthesized. 2RDNTPA exhibits a large Stokes shift of 244 nm and red fluorescence emission of 629 nm with a decent photoluminescence quantum yield of 13%. Furthermore, as a potential red fluorescent dye, 2RDNTPA can be applied in fluorescence imaging of living cancer cells (HepG2) with negligible cytotoxicity and a half maximal inhibitory concentration much more than 100 μM.

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EP - 163

JO - RSC Advances

JF - RSC Advances

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ER -

Design, synthesis and application in biological imaging of a novel red fluorescent dye based on a rhodanine derivative

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