DNA sensing by field-effect transistors based on networks of carbon nanotubes

Ling Gui Ee, Lain Jong Li, Keke Zhang, Yangping Xu, Xiaochen Dong, Xinning Ho, See Lee Pooi, Johnson Kasim, Z. X. Shen, John A. Rogers, S. G. Mhaisalkar

Research output: Contribution to journalArticlepeer-review

142 Scopus citations

Abstract

We report on the sensing mechanism of electrical detection of deoxyribonucleic acid (DNA) hybridization for Au- and Cr-contacted field effect transistors based on single-walled carbon nanotube (SWCNT) networks. Barrier height extraction via low-temperature electrical measurement provides direct evidence for the notion that the energy level alignment between electrode and SWCNTs can be affected by DNA immobilization and hybridization. The study of location-selective capping using photoresist provides comprehensive evidence that the sensing of DNA is dominated by the change in metal-SWCNT junctions rather than the channel conductance.

Original languageEnglish
Pages (from-to)14427-14432
Number of pages6
JournalJournal of the American Chemical Society
Volume129
Issue number46
DOIs
StatePublished - 21 Nov 2007
Externally publishedYes

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