Efficient synthesis of chromenopyridine and chromene via MCRs

Hai Feng Gan; Wei Wei Cao; Zheng Fang; Xin Li; Shi Gui Tang; Kai Guo

doi:10.1016/j.cclet.2014.05.008

Efficient synthesis of chromenopyridine and chromene via MCRs

Hai Feng Gan, Wei Wei Cao, Zheng Fang, Xin Li, Shi Gui Tang, Kai Guo

COLLEGE OF BIOTECHNOLOGY AND PHARMACEUTICAL ENGINEERING

Nanjing Tech University

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

MCRs for preparation of chromenopyridines under reflux conditions and chromenes at room temperature conditions from different salicylaldehydes, malononitrile and different thiols (mol ratio = 1:2:1) were established. Mechanistic investigation suggests that the MCRs undergo different pathways at different temperatures and catalyzed by different organic bases. The structure of chromenopyridine and chromene are confirmed by crystal X-ray crystallography.

Original language	English
Pages (from-to)	1357-1362
Number of pages	6
Journal	Chinese Chemical Letters
Volume	25
Issue number	10
DOIs	https://doi.org/10.1016/j.cclet.2014.05.008
State	Published - Oct 2014

Keywords

Chromene
Chromenopyridine
Mechanistic study
Multi-component reaction
Reaction condition

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10.1016/j.cclet.2014.05.008

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title = "Efficient synthesis of chromenopyridine and chromene via MCRs",

abstract = "MCRs for preparation of chromenopyridines under reflux conditions and chromenes at room temperature conditions from different salicylaldehydes, malononitrile and different thiols (mol ratio = 1:2:1) were established. Mechanistic investigation suggests that the MCRs undergo different pathways at different temperatures and catalyzed by different organic bases. The structure of chromenopyridine and chromene are confirmed by crystal X-ray crystallography.",

keywords = "Chromene, Chromenopyridine, Mechanistic study, Multi-component reaction, Reaction condition",

author = "Gan, {Hai Feng} and Cao, {Wei Wei} and Zheng Fang and Xin Li and Tang, {Shi Gui} and Kai Guo",

year = "2014",

month = oct,

doi = "10.1016/j.cclet.2014.05.008",

language = "英语",

volume = "25",

pages = "1357--1362",

journal = "Chinese Chemical Letters",

issn = "1001-8417",

publisher = "Elsevier B.V.",

number = "10",

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TY - JOUR

T1 - Efficient synthesis of chromenopyridine and chromene via MCRs

AU - Gan, Hai Feng

AU - Cao, Wei Wei

AU - Fang, Zheng

AU - Li, Xin

AU - Tang, Shi Gui

AU - Guo, Kai

PY - 2014/10

Y1 - 2014/10

N2 - MCRs for preparation of chromenopyridines under reflux conditions and chromenes at room temperature conditions from different salicylaldehydes, malononitrile and different thiols (mol ratio = 1:2:1) were established. Mechanistic investigation suggests that the MCRs undergo different pathways at different temperatures and catalyzed by different organic bases. The structure of chromenopyridine and chromene are confirmed by crystal X-ray crystallography.

AB - MCRs for preparation of chromenopyridines under reflux conditions and chromenes at room temperature conditions from different salicylaldehydes, malononitrile and different thiols (mol ratio = 1:2:1) were established. Mechanistic investigation suggests that the MCRs undergo different pathways at different temperatures and catalyzed by different organic bases. The structure of chromenopyridine and chromene are confirmed by crystal X-ray crystallography.

KW - Chromene

KW - Chromenopyridine

KW - Mechanistic study

KW - Multi-component reaction

KW - Reaction condition

UR - http://www.scopus.com/inward/record.url?scp=84921048521&partnerID=8YFLogxK

U2 - 10.1016/j.cclet.2014.05.008

DO - 10.1016/j.cclet.2014.05.008

M3 - 文章

AN - SCOPUS:84921048521

SN - 1001-8417

VL - 25

SP - 1357

EP - 1362

JO - Chinese Chemical Letters

JF - Chinese Chemical Letters

IS - 10

ER -

Efficient synthesis of chromenopyridine and chromene via MCRs

Abstract

Keywords

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