TY - JOUR
T1 - Facile fabrication of novel konjac glucomannan films with antibacterial properties via microfluidic spinning strategy
AU - Ni, Yongsheng
AU - Lin, Wanmei
AU - Mu, Ruojun
AU - Wu, Chunhua
AU - Lin, Zheya
AU - Chen, Su
AU - Pang, Jie
N1 - Publisher Copyright:
© 2019 Elsevier Ltd
PY - 2019/3/15
Y1 - 2019/3/15
N2 - The exploration of methods to produce biomaterials with antibacterial properties in ultra-small scales is of great scientific and technological interest. Here, we reported a microfluidic spinning approach to prepare a novel film combined with konjac glucomannan (KGM), polyvinylpyrrolidone (PVP), and epigallocatechin gallate (EGCG). The film was characterized by scanning electron microscopy, Fourier transform infrared spectroscopy, X-ray diffraction, and thermogravimetric analysis. This film was transparent, orderly, thermally stable, and uniform in size, with an average width less than 1 μm. Also, the film exhibited excellent antibacterial efficiency (97.1% against E. coli, 99.7% against S. aureus, 97.3% against S. enterica and 99.9% against B. subtilis) in our antibacterial test. In addition, the film promoted wound healing with the advanced development of neovascularization and hair follicles. This strategy provides a facile and green pathway for the construction of biomaterial films for medical applications.
AB - The exploration of methods to produce biomaterials with antibacterial properties in ultra-small scales is of great scientific and technological interest. Here, we reported a microfluidic spinning approach to prepare a novel film combined with konjac glucomannan (KGM), polyvinylpyrrolidone (PVP), and epigallocatechin gallate (EGCG). The film was characterized by scanning electron microscopy, Fourier transform infrared spectroscopy, X-ray diffraction, and thermogravimetric analysis. This film was transparent, orderly, thermally stable, and uniform in size, with an average width less than 1 μm. Also, the film exhibited excellent antibacterial efficiency (97.1% against E. coli, 99.7% against S. aureus, 97.3% against S. enterica and 99.9% against B. subtilis) in our antibacterial test. In addition, the film promoted wound healing with the advanced development of neovascularization and hair follicles. This strategy provides a facile and green pathway for the construction of biomaterial films for medical applications.
KW - Antibacterial properties
KW - Films
KW - Konjac glucomannan
KW - Microfluidic spinning technology
KW - Wound healing
UR - http://www.scopus.com/inward/record.url?scp=85059453001&partnerID=8YFLogxK
U2 - 10.1016/j.carbpol.2018.12.102
DO - 10.1016/j.carbpol.2018.12.102
M3 - 文章
C2 - 30658825
AN - SCOPUS:85059453001
SN - 0144-8617
VL - 208
SP - 469
EP - 476
JO - Carbohydrate Polymers
JF - Carbohydrate Polymers
ER -