Few-Layer Graphdiyne Nanosheets Applied for Multiplexed Real-Time DNA Detection

Nargish Parvin; Quan Jin; Yanze Wei; Ranbo Yu; Bing Zheng; Ling Huang; Ying Zhang; Lianhui Wang; Hua Zhang; Mingyuan Gao; Huijun Zhao; Wenping Hu; Yuliang Li; Dan Wang

doi:10.1002/adma.201606755

Few-Layer Graphdiyne Nanosheets Applied for Multiplexed Real-Time DNA Detection

Nargish Parvin, Quan Jin, Yanze Wei, Ranbo Yu, Bing Zheng, Ling Huang, Ying Zhang, Lianhui Wang, Hua Zhang, Mingyuan Gao, Huijun Zhao, Wenping Hu, Yuliang Li, Dan Wang

SCHOOL OF FLEXIBLE ELECTRONICS(FUTURE TECHNOLOGIES)|INSTITUTE OF ADVANCED MATERIALS(IAM)

Research output: Contribution to journal › Article › peer-review

215 Scopus citations

Abstract

Despite recent progress in 2D nanomaterials-based biosensing, it remains challenging to achieve sensitive and high selective detection. This study develops few-layer graphdiyne (GD) nanosheets (NSs) that are used as novel sensing platforms for a variety of fluorophores real-time detection of DNA with low background and high signal-to-noise ratio, which show a distinguished fluorescence quenching ability and different affinities toward single-stranded DNA and double-stranded DNA. Importantly, for the first time, a few-layer GD NSs-based multiplexed DNA sensor is developed.

Original language	English
Article number	1606755
Journal	Advanced Materials
Volume	29
Issue number	18
DOIs	https://doi.org/10.1002/adma.201606755
State	Published - 10 May 2017

Keywords

biosensing
fluorescence quenching
graphdiyne nanosheets
real-time detection

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title = "Few-Layer Graphdiyne Nanosheets Applied for Multiplexed Real-Time DNA Detection",

abstract = "Despite recent progress in 2D nanomaterials-based biosensing, it remains challenging to achieve sensitive and high selective detection. This study develops few-layer graphdiyne (GD) nanosheets (NSs) that are used as novel sensing platforms for a variety of fluorophores real-time detection of DNA with low background and high signal-to-noise ratio, which show a distinguished fluorescence quenching ability and different affinities toward single-stranded DNA and double-stranded DNA. Importantly, for the first time, a few-layer GD NSs-based multiplexed DNA sensor is developed.",

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T1 - Few-Layer Graphdiyne Nanosheets Applied for Multiplexed Real-Time DNA Detection

AU - Parvin, Nargish

AU - Jin, Quan

AU - Wei, Yanze

AU - Yu, Ranbo

AU - Zheng, Bing

AU - Huang, Ling

AU - Zhang, Ying

AU - Wang, Lianhui

AU - Zhang, Hua

AU - Gao, Mingyuan

AU - Zhao, Huijun

AU - Hu, Wenping

AU - Li, Yuliang

AU - Wang, Dan

PY - 2017/5/10

Y1 - 2017/5/10

N2 - Despite recent progress in 2D nanomaterials-based biosensing, it remains challenging to achieve sensitive and high selective detection. This study develops few-layer graphdiyne (GD) nanosheets (NSs) that are used as novel sensing platforms for a variety of fluorophores real-time detection of DNA with low background and high signal-to-noise ratio, which show a distinguished fluorescence quenching ability and different affinities toward single-stranded DNA and double-stranded DNA. Importantly, for the first time, a few-layer GD NSs-based multiplexed DNA sensor is developed.

AB - Despite recent progress in 2D nanomaterials-based biosensing, it remains challenging to achieve sensitive and high selective detection. This study develops few-layer graphdiyne (GD) nanosheets (NSs) that are used as novel sensing platforms for a variety of fluorophores real-time detection of DNA with low background and high signal-to-noise ratio, which show a distinguished fluorescence quenching ability and different affinities toward single-stranded DNA and double-stranded DNA. Importantly, for the first time, a few-layer GD NSs-based multiplexed DNA sensor is developed.

KW - biosensing

KW - fluorescence quenching

KW - graphdiyne nanosheets

KW - real-time detection

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DO - 10.1002/adma.201606755

M3 - 文章

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Few-Layer Graphdiyne Nanosheets Applied for Multiplexed Real-Time DNA Detection

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Keywords

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