TY - JOUR
T1 - Fine-needle aspiration with rapid parathyroid hormone assay to identify parathyroid gland in thyroidectomy
AU - Zou, Xian
AU - Shi, Longshun
AU - Zhu, Guohua
AU - Zhu, Liguo
AU - Bao, Jiandong
AU - Fan, Jun
AU - Hu, Yonghong
AU - Zhou, Bin
AU - Lv, Zhongwei
N1 - Publisher Copyright:
Copyright © 2020 the Author(s). Published by Wolters Kluwer Health, Inc.
PY - 2020/4/24
Y1 - 2020/4/24
N2 - To determine the levels of parathyroid hormone (PTH) in the fluids of various tissues for identification of parathyroid glands during thyroidectomy.Our study comprised 31 patients with thyroid cancer who underwent lobectomy with central compartment dissection at our hospital from October 2014 to February 2015. A total of 186 tissue samples, including 28 from parathyroid glands and 158 from non-parathyroid tissues, were obtained during the operations. Tissue fluids were collected via fine-needle aspiration to measure PTH levels; the tissue was punctured 3 times with a 26-gauge syringe needle and washed with 0.5 mL normal saline. Tissues were also prepared for pathological examination.PTH concentrations were significantly higher in parathyroid tissues than non-parathyroid tissues. None of the patients had irremediable parathyroid dysfunction after surgical resection.Use of fine-needle aspiration for quantification of PTH levels in tissue fluids rapidly, safely, and effectively identifies the parathyroid glands during thyroidectomy.
AB - To determine the levels of parathyroid hormone (PTH) in the fluids of various tissues for identification of parathyroid glands during thyroidectomy.Our study comprised 31 patients with thyroid cancer who underwent lobectomy with central compartment dissection at our hospital from October 2014 to February 2015. A total of 186 tissue samples, including 28 from parathyroid glands and 158 from non-parathyroid tissues, were obtained during the operations. Tissue fluids were collected via fine-needle aspiration to measure PTH levels; the tissue was punctured 3 times with a 26-gauge syringe needle and washed with 0.5 mL normal saline. Tissues were also prepared for pathological examination.PTH concentrations were significantly higher in parathyroid tissues than non-parathyroid tissues. None of the patients had irremediable parathyroid dysfunction after surgical resection.Use of fine-needle aspiration for quantification of PTH levels in tissue fluids rapidly, safely, and effectively identifies the parathyroid glands during thyroidectomy.
KW - central compartment lymph node dissection
KW - intraoperative parathyroid hormone levels
KW - parathyroid preservation
UR - http://www.scopus.com/inward/record.url?scp=85086496174&partnerID=8YFLogxK
U2 - 10.1097/MD.0000000000019840
DO - 10.1097/MD.0000000000019840
M3 - 文章
C2 - 32312007
AN - SCOPUS:85086496174
SN - 0025-7974
VL - 99
SP - E19840
JO - Medicine (United States)
JF - Medicine (United States)
IS - 16
ER -
