Fluorescent and luminescent probes for detection of reactive oxygen and nitrogen species

Xiaoqiang Chen, Xizhe Tian, Injae Shin, Juyoung Yoon

Research output: Contribution to journalArticlepeer-review

907 Scopus citations

Abstract

Oxidative and nitrosative stress induced by ROS/RNS play crucial roles in a wide range of physiological processes and are also implicated in various diseases, including cancer and neurodegenerative disorders. Sensitive and selective methods for the detection of ROS/RNS based on fluorescent and luminescent probes are of great use in monitoring the in vivo production of these species and elucidating their biological functions. This critical review highlights recent advances that have been made in the development of fluorescent and luminescent probes employed to monitor various ROS/RNS (132 references).

Original languageEnglish
Pages (from-to)4783-4804
Number of pages22
JournalChemical Society Reviews
Volume40
Issue number9
DOIs
StatePublished - 15 Aug 2011

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