In Situ-Forming Magnetic Fe₃O₄Nanoroses on Defect-Controllable Mesoporous Graphene Oxide for Enzyme-Mimic Sensing

Glucose detection is always a central issue for researchers due to its comprehensive use in the fermentation industry, food industry, and biomedical industry. Due to the easy activity loss and poor stability of the enzymatic sensor, the development of a nonenzymatic sensor is a desired substitution for target recognition. But working under a low alkaline environment with high performance is always a challenge. To address the above issue, an enzymatic oxidation method was used to design a rose-like nano-Fe3O4/GO film to mimic the catalytic function of glucose oxidase. Abundant porous defects with increased oxygen-containing groups were created on the GO surface, and then Fe3O4 crystals were constrained to grow surrounding the defective sites. The rose-like morphology provides an ultrahigh specific surface area to effectively capture OH-, which shows excellent sensitivities of glucose detection in varied pH environments from 9 to 13 at a very low operation potential.