Indium (Zinc)-copper-mediated barbier-type alkylation reaction of nitrones in water: Synthesis of amines and hydroxylamines

Yong Sheng Yang; Zhi Liang Shen; Teck Peng Loh

doi:10.1021/ol8027362

Indium (Zinc)-copper-mediated barbier-type alkylation reaction of nitrones in water: Synthesis of amines and hydroxylamines

Yong Sheng Yang, Zhi Liang Shen, Teck Peng Loh

Nanyang Technological University

Research output: Contribution to journal › Article › peer-review

35 Scopus citations

Abstract

An efficient method for the Barbier-type alkylation reaction of various nitrones (including chiral version) and alkyl halides in water is described. The amines and hydroxylamines can be obtained in good yields, depending on the judicious choice of the metal complexes used.

Original language	English
Pages (from-to)	1209-1212
Number of pages	4
Journal	Organic Letters
Volume	11
Issue number	6
DOIs	https://doi.org/10.1021/ol8027362
State	Published - 19 Mar 2009
Externally published	Yes

Access to Document

10.1021/ol8027362

Cite this

@article{040fea46d41344d291a239fcea4bcc06,

title = "Indium (Zinc)-copper-mediated barbier-type alkylation reaction of nitrones in water: Synthesis of amines and hydroxylamines",

abstract = "An efficient method for the Barbier-type alkylation reaction of various nitrones (including chiral version) and alkyl halides in water is described. The amines and hydroxylamines can be obtained in good yields, depending on the judicious choice of the metal complexes used.",

author = "Yang, {Yong Sheng} and Shen, {Zhi Liang} and Loh, {Teck Peng}",

year = "2009",

month = mar,

day = "19",

doi = "10.1021/ol8027362",

language = "英语",

volume = "11",

pages = "1209--1212",

journal = "Organic Letters",

issn = "1523-7060",

publisher = "American Chemical Society",

number = "6",

}

TY - JOUR

T1 - Indium (Zinc)-copper-mediated barbier-type alkylation reaction of nitrones in water

T2 - Synthesis of amines and hydroxylamines

AU - Yang, Yong Sheng

AU - Shen, Zhi Liang

AU - Loh, Teck Peng

PY - 2009/3/19

Y1 - 2009/3/19

N2 - An efficient method for the Barbier-type alkylation reaction of various nitrones (including chiral version) and alkyl halides in water is described. The amines and hydroxylamines can be obtained in good yields, depending on the judicious choice of the metal complexes used.

AB - An efficient method for the Barbier-type alkylation reaction of various nitrones (including chiral version) and alkyl halides in water is described. The amines and hydroxylamines can be obtained in good yields, depending on the judicious choice of the metal complexes used.

UR - http://www.scopus.com/inward/record.url?scp=64349116710&partnerID=8YFLogxK

U2 - 10.1021/ol8027362

DO - 10.1021/ol8027362

M3 - 文章

AN - SCOPUS:64349116710

SN - 1523-7060

VL - 11

SP - 1209

EP - 1212

JO - Organic Letters

JF - Organic Letters

IS - 6

ER -

Indium (Zinc)-copper-mediated barbier-type alkylation reaction of nitrones in water: Synthesis of amines and hydroxylamines

Abstract

Access to Document

Other files and links

Fingerprint

Cite this