Intermolecular proton transfer from flavonol to human serum albumin triggers a red-shifted ratiometric fluorescence response

Zhongyong Xu; Mingyuan Zhang; Zihao Chen; Yutian Zhao; Lei Wang; Xiaoqiang Chen; Bin Liu; Xiaojun Peng

doi:10.1039/d3cc01546g

Intermolecular proton transfer from flavonol to human serum albumin triggers a red-shifted ratiometric fluorescence response

Zhongyong Xu, Mingyuan Zhang, Zihao Chen, Yutian Zhao, Lei Wang, Xiaoqiang Chen, Bin Liu, Xiaojun Peng

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

Intermolecular proton transfer from a flavonol-based probe to the arginine (Arg222) in drug site 1 of human serum albumin triggers an unusual red-shifted ratiometric fluorescence response, which can be applied in the point-to-care diagnosis of hypoalbuminemia.

Original language	English
Pages (from-to)	5775-5778
Number of pages	4
Journal	Chemical Communications
Volume	59
Issue number	38
DOIs	https://doi.org/10.1039/d3cc01546g
State	Published - 19 Apr 2023
Externally published	Yes

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title = "Intermolecular proton transfer from flavonol to human serum albumin triggers a red-shifted ratiometric fluorescence response",

abstract = "Intermolecular proton transfer from a flavonol-based probe to the arginine (Arg222) in drug site 1 of human serum albumin triggers an unusual red-shifted ratiometric fluorescence response, which can be applied in the point-to-care diagnosis of hypoalbuminemia.",

author = "Zhongyong Xu and Mingyuan Zhang and Zihao Chen and Yutian Zhao and Lei Wang and Xiaoqiang Chen and Bin Liu and Xiaojun Peng",

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doi = "10.1039/d3cc01546g",

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T1 - Intermolecular proton transfer from flavonol to human serum albumin triggers a red-shifted ratiometric fluorescence response

AU - Xu, Zhongyong

AU - Zhang, Mingyuan

AU - Chen, Zihao

AU - Zhao, Yutian

AU - Wang, Lei

AU - Chen, Xiaoqiang

AU - Liu, Bin

AU - Peng, Xiaojun

PY - 2023/4/19

Y1 - 2023/4/19

N2 - Intermolecular proton transfer from a flavonol-based probe to the arginine (Arg222) in drug site 1 of human serum albumin triggers an unusual red-shifted ratiometric fluorescence response, which can be applied in the point-to-care diagnosis of hypoalbuminemia.

AB - Intermolecular proton transfer from a flavonol-based probe to the arginine (Arg222) in drug site 1 of human serum albumin triggers an unusual red-shifted ratiometric fluorescence response, which can be applied in the point-to-care diagnosis of hypoalbuminemia.

UR - http://www.scopus.com/inward/record.url?scp=85153965183&partnerID=8YFLogxK

U2 - 10.1039/d3cc01546g

DO - 10.1039/d3cc01546g

M3 - 文章

C2 - 37096416

AN - SCOPUS:85153965183

SN - 1359-7345

VL - 59

SP - 5775

EP - 5778

JO - Chemical Communications

JF - Chemical Communications

IS - 38

ER -

Intermolecular proton transfer from flavonol to human serum albumin triggers a red-shifted ratiometric fluorescence response

Abstract

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