Intrinsic kinetics of ammoximation of acetone with hydrogen peroxide catalyzed by TS-1

Acetone oxime is an excellent deoxidant, and its preparation by acetone ammoximation over catalyst titanium silicalites-1 (TS-1) is a novel environmentally friendly technology. Using ammonia and hydrogen peroxide as the ammoximation agents, the intrinsic kinetics of the acetone ammoximation reaction over catalyst TS-1 to produce acetone oxime was investigated by the help of high-performance liquid chromatography (HPLC) technique. In our experiments, since the average particle size of the used TS-1 catalyst is about 200 nm, and the used stirring rates are over 580 r·min^-1, both the effects of internal diffusion resistance and external diffusion on the ammoximation reaction can be ignored and the reaction is controlled only by the kinetics of ammoximation. Through the experiments, the orders of the reaction were found to be 0.87 with respect to acetone, 0.05 with respect to H₂O₂ and 1.0 with respect to NH₃, respectively. The reaction activation energy found is 101.88 kJ·mol^-1 and the pre-exponential factor found is 5.20 × 10¹³ mol^-0.92·L^0.92min^-1. This study provides the fundamental data for preparing the acetone oxime by the process coupling the catalytic reaction over TS-1 with its membrane separation.