Iron-Catalyzed Aerobic α,β-Dehydrogenation

Guo Qing Jiang; Bin Hong Han; Xian Peng Cai; Jian Ping Qu; Yan Biao Kang

doi:10.1021/acs.orglett.3c01240

Iron-Catalyzed Aerobic α,β-Dehydrogenation

Guo Qing Jiang, Bin Hong Han, Xian Peng Cai, Jian Ping Qu, Yan Biao Kang

School of Chemistry and Moleculai Engineering

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

An iron-catalyzed direct aerobic α,β-dehydrogenation of carbonyls has been reported. The combination of tert-butyl nitrite and N-hydroxyphthalimide worked as the organo cocatalyst system; thus, no extra transition metal reagents are required. A large variety of lactams and flavanones as well as lactone and thiochromen-4-one could be produced via this method in high yields.

Original language	English
Pages (from-to)	4429-4433
Number of pages	5
Journal	Organic Letters
Volume	25
Issue number	24
DOIs	https://doi.org/10.1021/acs.orglett.3c01240
State	Published - 23 Jun 2023

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10.1021/acs.orglett.3c01240

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abstract = "An iron-catalyzed direct aerobic α,β-dehydrogenation of carbonyls has been reported. The combination of tert-butyl nitrite and N-hydroxyphthalimide worked as the organo cocatalyst system; thus, no extra transition metal reagents are required. A large variety of lactams and flavanones as well as lactone and thiochromen-4-one could be produced via this method in high yields.",

author = "Jiang, {Guo Qing} and Han, {Bin Hong} and Cai, {Xian Peng} and Qu, {Jian Ping} and Kang, {Yan Biao}",

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AU - Jiang, Guo Qing

AU - Han, Bin Hong

AU - Cai, Xian Peng

AU - Qu, Jian Ping

AU - Kang, Yan Biao

PY - 2023/6/23

Y1 - 2023/6/23

N2 - An iron-catalyzed direct aerobic α,β-dehydrogenation of carbonyls has been reported. The combination of tert-butyl nitrite and N-hydroxyphthalimide worked as the organo cocatalyst system; thus, no extra transition metal reagents are required. A large variety of lactams and flavanones as well as lactone and thiochromen-4-one could be produced via this method in high yields.

AB - An iron-catalyzed direct aerobic α,β-dehydrogenation of carbonyls has been reported. The combination of tert-butyl nitrite and N-hydroxyphthalimide worked as the organo cocatalyst system; thus, no extra transition metal reagents are required. A large variety of lactams and flavanones as well as lactone and thiochromen-4-one could be produced via this method in high yields.

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DO - 10.1021/acs.orglett.3c01240

M3 - 文章

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SP - 4429

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JO - Organic Letters

JF - Organic Letters

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ER -

Iron-Catalyzed Aerobic α,β-Dehydrogenation

Abstract

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