KI-Promoted Oxidative Coupling of Styrenes with Indoles under Metal-Free Conditions: Facile Access to C-3 Dicarbonyl Indoles

Bochao Zhou; Shiyu Guo; Zheng Fang; Zhao Yang; Chengkou Liu; Wei He; Ning Zhu; Xin Li; Kai Guo

doi:10.1055/s-0037-1611888

KI-Promoted Oxidative Coupling of Styrenes with Indoles under Metal-Free Conditions: Facile Access to C-3 Dicarbonyl Indoles

Bochao Zhou, Shiyu Guo, Zheng Fang, Zhao Yang, Chengkou Liu, Wei He, Ning Zhu, Xin Li, Kai Guo

COLLEGE OF BIOTECHNOLOGY AND PHARMACEUTICAL ENGINEERING

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

A new and efficient method for the synthesis of C-3 dicarbonyl indoles via oxidative cross-coupling of styrenes with indoles under metal-free conditions has been developed. Moreover, a broad scope of C-3 dicarbonyl indoles in moderate to good yields were obtained, and a plausible mechanism is proposed based on control and isotope-labeling experiments.

Original language	English
Article number	ss-2019-h0268-op
Pages (from-to)	3511-3519
Number of pages	9
Journal	Synthesis (Germany)
Volume	51
Issue number	18
DOIs	https://doi.org/10.1055/s-0037-1611888
State	Published - 2019

Keywords

dicarbonyl indoles
metal free
styrenes
synthetic methods

Access to Document

10.1055/s-0037-1611888

Cite this

@article{033739257457403cbf5c4bca70b9b637,

title = "KI-Promoted Oxidative Coupling of Styrenes with Indoles under Metal-Free Conditions: Facile Access to C-3 Dicarbonyl Indoles",

abstract = "A new and efficient method for the synthesis of C-3 dicarbonyl indoles via oxidative cross-coupling of styrenes with indoles under metal-free conditions has been developed. Moreover, a broad scope of C-3 dicarbonyl indoles in moderate to good yields were obtained, and a plausible mechanism is proposed based on control and isotope-labeling experiments.",

keywords = "dicarbonyl indoles, metal free, styrenes, synthetic methods",

author = "Bochao Zhou and Shiyu Guo and Zheng Fang and Zhao Yang and Chengkou Liu and Wei He and Ning Zhu and Xin Li and Kai Guo",

note = "Publisher Copyright: {\textcopyright} Georg Thieme Verlag Stuttgart New York.",

year = "2019",

doi = "10.1055/s-0037-1611888",

language = "英语",

volume = "51",

pages = "3511--3519",

journal = "Synthesis (Germany)",

issn = "0039-7881",

publisher = "Georg Thieme Verlag",

number = "18",

}

TY - JOUR

T1 - KI-Promoted Oxidative Coupling of Styrenes with Indoles under Metal-Free Conditions

T2 - Facile Access to C-3 Dicarbonyl Indoles

AU - Zhou, Bochao

AU - Guo, Shiyu

AU - Fang, Zheng

AU - Yang, Zhao

AU - Liu, Chengkou

AU - He, Wei

AU - Zhu, Ning

AU - Li, Xin

AU - Guo, Kai

N1 - Publisher Copyright: © Georg Thieme Verlag Stuttgart New York.

PY - 2019

Y1 - 2019

N2 - A new and efficient method for the synthesis of C-3 dicarbonyl indoles via oxidative cross-coupling of styrenes with indoles under metal-free conditions has been developed. Moreover, a broad scope of C-3 dicarbonyl indoles in moderate to good yields were obtained, and a plausible mechanism is proposed based on control and isotope-labeling experiments.

AB - A new and efficient method for the synthesis of C-3 dicarbonyl indoles via oxidative cross-coupling of styrenes with indoles under metal-free conditions has been developed. Moreover, a broad scope of C-3 dicarbonyl indoles in moderate to good yields were obtained, and a plausible mechanism is proposed based on control and isotope-labeling experiments.

KW - dicarbonyl indoles

KW - metal free

KW - styrenes

KW - synthetic methods

UR - http://www.scopus.com/inward/record.url?scp=85071680825&partnerID=8YFLogxK

U2 - 10.1055/s-0037-1611888

DO - 10.1055/s-0037-1611888

M3 - 文章

AN - SCOPUS:85071680825

SN - 0039-7881

VL - 51

SP - 3511

EP - 3519

JO - Synthesis (Germany)

JF - Synthesis (Germany)

IS - 18

M1 - ss-2019-h0268-op

ER -

KI-Promoted Oxidative Coupling of Styrenes with Indoles under Metal-Free Conditions: Facile Access to C-3 Dicarbonyl Indoles

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this