Kinetics of adsorption of thymopentin on a gel-type strong cation-exchange resin

The ion-exchange kinetics have been determined for adsorption of thymopentin on a gel-type sulfonated styrene-divinylbenzene resin converted to the ammonium form. Batch equilibrium and kinetic experiments were performed in chloride ion solutions of different concentration. Equilibrium data revealed isotherms were a good fit to the constant separation factor isotherm. Because of the high capacity and low cost of the resin its use for uptake of thymopentin was economically feasible. Kinetic data were compared with the predictions from the Nernst-Planck and Fick models. The intraparticle and effective diffusivity of thymopentin were obtained from these models.