Multi-component reaction based on isocyanides

Xuewei Liu, Haifen Gan, Xiangjun Qian, Baohua Zou, Hui Zhong, Kai Guo

Research output: Contribution to journalArticlepeer-review

Abstract

Multi-component reactions (MCRs) have attracted lots of interest and been the focus of many synthetic chemists due to their intrinsic economic and ecological value. Since both electrophilic reaction and nucleophilic reaction are performed via the carbon atom, isocyanide plays a significant role in MCRs. In this paper, progresses of MCRs involved isocyanide in recent years, especially about the mechanism, research progress and application of Ugi reactions and Passerini reactions were discussed.

Original languageEnglish
Pages (from-to)107-112
Number of pages6
JournalChemistry Bulletin / Huaxue Tongbao
Volume76
Issue number2
StatePublished - Feb 2013

Keywords

  • Isocyanide
  • Multi-component reactions
  • Passerini reaction
  • Ugi reaction

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