Multicomponent reactions for the synthesis of new 3′-indolyl substituted heterocycles under microwave irradiation

Song Lei Zhu; Shun Jun Ji; Kai Zhao; Yu Liu

doi:10.1016/j.tetlet.2008.02.101

Multicomponent reactions for the synthesis of new 3′-indolyl substituted heterocycles under microwave irradiation

Song Lei Zhu, Shun Jun Ji, Kai Zhao, Yu Liu

Research output: Contribution to journal › Article › peer-review

77 Scopus citations

Abstract

A series of polysubstituted (3′-indolyl)pyrazolo[3,4-b]pyridine and (3′-indolyl)benzo[h]quinoline derivatives were synthesized via one-pot multicomponent reactions of aldehydes, 3-cyanoacetyl indoles with 5-aminopyrazol or naphthylamine under microwave irradiation. Particularly valuable features of this method include high yields of products, broad substrate scope, short reaction time and straightforward procedure.

Original language	English
Pages (from-to)	2578-2582
Number of pages	5
Journal	Tetrahedron Letters
Volume	49
Issue number	16
DOIs	https://doi.org/10.1016/j.tetlet.2008.02.101
State	Published - 14 Apr 2008
Externally published	Yes

Keywords

Heterocycle
Indole
Microwave irradiation
Multicomponent reactions

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10.1016/j.tetlet.2008.02.101

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title = "Multicomponent reactions for the synthesis of new 3′-indolyl substituted heterocycles under microwave irradiation",

abstract = "A series of polysubstituted (3′-indolyl)pyrazolo[3,4-b]pyridine and (3′-indolyl)benzo[h]quinoline derivatives were synthesized via one-pot multicomponent reactions of aldehydes, 3-cyanoacetyl indoles with 5-aminopyrazol or naphthylamine under microwave irradiation. Particularly valuable features of this method include high yields of products, broad substrate scope, short reaction time and straightforward procedure.",

keywords = "Heterocycle, Indole, Microwave irradiation, Multicomponent reactions",

author = "Zhu, {Song Lei} and Ji, {Shun Jun} and Kai Zhao and Yu Liu",

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doi = "10.1016/j.tetlet.2008.02.101",

language = "英语",

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T1 - Multicomponent reactions for the synthesis of new 3′-indolyl substituted heterocycles under microwave irradiation

AU - Zhu, Song Lei

AU - Ji, Shun Jun

AU - Zhao, Kai

AU - Liu, Yu

PY - 2008/4/14

Y1 - 2008/4/14

N2 - A series of polysubstituted (3′-indolyl)pyrazolo[3,4-b]pyridine and (3′-indolyl)benzo[h]quinoline derivatives were synthesized via one-pot multicomponent reactions of aldehydes, 3-cyanoacetyl indoles with 5-aminopyrazol or naphthylamine under microwave irradiation. Particularly valuable features of this method include high yields of products, broad substrate scope, short reaction time and straightforward procedure.

AB - A series of polysubstituted (3′-indolyl)pyrazolo[3,4-b]pyridine and (3′-indolyl)benzo[h]quinoline derivatives were synthesized via one-pot multicomponent reactions of aldehydes, 3-cyanoacetyl indoles with 5-aminopyrazol or naphthylamine under microwave irradiation. Particularly valuable features of this method include high yields of products, broad substrate scope, short reaction time and straightforward procedure.

KW - Heterocycle

KW - Indole

KW - Microwave irradiation

KW - Multicomponent reactions

UR - http://www.scopus.com/inward/record.url?scp=40849097396&partnerID=8YFLogxK

U2 - 10.1016/j.tetlet.2008.02.101

DO - 10.1016/j.tetlet.2008.02.101

M3 - 文章

AN - SCOPUS:40849097396

SN - 0040-4039

VL - 49

SP - 2578

EP - 2582

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 16

ER -

Multicomponent reactions for the synthesis of new 3′-indolyl substituted heterocycles under microwave irradiation

Abstract

Keywords

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