Nickel-Catalyzed Diastereoselective Reductive Cross-Coupling of Disubstituted Cycloalkyl Iodides with Aryl Iodides

Xuan Di Song; Meng Meng Guo; Shuang Xu; Chuanji Shen; Xiaocong Zhou; Xue Qiang Chu; Mengtao Ma; Zhi Liang Shen

doi:10.1021/acs.orglett.1c01649

Nickel-Catalyzed Diastereoselective Reductive Cross-Coupling of Disubstituted Cycloalkyl Iodides with Aryl Iodides

Xuan Di Song, Meng Meng Guo, Shuang Xu, Chuanji Shen, Xiaocong Zhou, Xue Qiang Chu, Mengtao Ma, Zhi Liang Shen

School of Chemistry and Moleculai Engineering

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

Abstract

A nickel-catalyzed direct reductive cross-coupling of disubstituted cycloalkyl iodides with aryl iodides was developed. The one-pot reaction, which is simple to operate, was capable of proceeding efficiently in a stereocontrolled manner to afford a variety of cross-coupled products with high diastereoselectivity and wide functional group tolerance.

Original language	English
Pages (from-to)	5118-5122
Number of pages	5
Journal	Organic Letters
Volume	23
Issue number	13
DOIs	https://doi.org/10.1021/acs.orglett.1c01649
State	Published - 2 Jul 2021

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abstract = "A nickel-catalyzed direct reductive cross-coupling of disubstituted cycloalkyl iodides with aryl iodides was developed. The one-pot reaction, which is simple to operate, was capable of proceeding efficiently in a stereocontrolled manner to afford a variety of cross-coupled products with high diastereoselectivity and wide functional group tolerance.",

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T1 - Nickel-Catalyzed Diastereoselective Reductive Cross-Coupling of Disubstituted Cycloalkyl Iodides with Aryl Iodides

AU - Song, Xuan Di

AU - Guo, Meng Meng

AU - Xu, Shuang

AU - Shen, Chuanji

AU - Zhou, Xiaocong

AU - Chu, Xue Qiang

AU - Ma, Mengtao

AU - Shen, Zhi Liang

PY - 2021/7/2

Y1 - 2021/7/2

N2 - A nickel-catalyzed direct reductive cross-coupling of disubstituted cycloalkyl iodides with aryl iodides was developed. The one-pot reaction, which is simple to operate, was capable of proceeding efficiently in a stereocontrolled manner to afford a variety of cross-coupled products with high diastereoselectivity and wide functional group tolerance.

AB - A nickel-catalyzed direct reductive cross-coupling of disubstituted cycloalkyl iodides with aryl iodides was developed. The one-pot reaction, which is simple to operate, was capable of proceeding efficiently in a stereocontrolled manner to afford a variety of cross-coupled products with high diastereoselectivity and wide functional group tolerance.

UR - http://www.scopus.com/inward/record.url?scp=85110260693&partnerID=8YFLogxK

U2 - 10.1021/acs.orglett.1c01649

DO - 10.1021/acs.orglett.1c01649

M3 - 文章

C2 - 34160224

AN - SCOPUS:85110260693

SN - 1523-7060

VL - 23

SP - 5118

EP - 5122

JO - Organic Letters

JF - Organic Letters

IS - 13

ER -

Nickel-Catalyzed Diastereoselective Reductive Cross-Coupling of Disubstituted Cycloalkyl Iodides with Aryl Iodides

Abstract

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