Novel one-pot Mannich-type reaction in water: Indium trichloride-catalyzed condensation of aldehydes, amines and silyl enol ethers for the synthesis of β-amino ketones and esters

Teck Peng Loh, Lin Li Wei

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163 Scopus citations

Abstract

Novel one-pot Mannich-type reaction between aldehydes, amines and silyl enol ethers is catalyzed by indium trichloride in water to give β-amino ketones and esters in moderate to good yields.

Original languageEnglish
Pages (from-to)323-326
Number of pages4
JournalTetrahedron Letters
Volume39
Issue number3-4
DOIs
StatePublished - 15 Jan 1998
Externally publishedYes

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