Palladium-Catalyzed Direct Intramolecular C-N Bond Formation: Access to Multisubstituted Dihydropyrroles

Bing Jiang, Fei Fan Meng, Qiu Ju Liang, Yun He Xu, Teck Peng Loh

Research output: Contribution to journalArticlepeer-review

32 Scopus citations

Abstract

A palladium-catalyzed intramolecular amination of alkenes with retention of olefin functionalization was achieved under mild reaction conditions. In the presence of palladium catalyst, the tosyl-protected amine can directly couple with a double bond to provide versatile dihydropyrrole derivatives in moderate to excellent yields.

Original languageEnglish
Pages (from-to)914-917
Number of pages4
JournalOrganic Letters
Volume19
Issue number4
DOIs
StatePublished - 17 Feb 2017
Externally publishedYes

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