Pd(II)-catalyzed C-H iodination using molecular I2 as the sole oxidant

Xiao Chen Wang, Yi Hu, Samuel Bonacorsi, Yang Hong, Richard Burrell, Jin Quan Yu

Research output: Contribution to journalArticlepeer-review

167 Scopus citations

Abstract

Pd-catalyzed ortho-C-H iodination directed by a weakly coordinating amide auxiliary using I2 as the sole oxidant was developed. This reaction is compatible with a wide range of heterocycles including pyridines, imidazoles, oxazoles, thiazoles, isoxazoles, and pyrazoles.

Original languageEnglish
Pages (from-to)10326-10329
Number of pages4
JournalJournal of the American Chemical Society
Volume135
Issue number28
DOIs
StatePublished - 17 Jul 2013
Externally publishedYes

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