Phenothiazine-aminothiourea-Hg(II) ensemble-based fluorescence turn-on toward iodide in aqueous media and imaging application in live cells

Wenge Yang; Shouhai Yang; Qirun Guo; Tuan Zhang; Keyi Wu; Yonghong Hu

doi:10.1016/j.snb.2015.02.117

Phenothiazine-aminothiourea-Hg(II) ensemble-based fluorescence turn-on toward iodide in aqueous media and imaging application in live cells

Wenge Yang, Shouhai Yang, Qirun Guo, Tuan Zhang, Keyi Wu, Yonghong Hu

Research output: Contribution to journal › Article › peer-review

42 Scopus citations

Abstract

A phenothiazine-aminothiourea-based open chemosensor (P1) has been designed and synthesized, which exhibits high selectivity toward Hg²⁺ by forming a 1:1 complex. In its Hg²⁺ ensemble, it is reported as a highly sensitive and selective probe for the detection of iodide based on the displacement approach in aqueous solution. The addition of iodide to a solution of phenothiazine-aminothiourea-Hg²⁺ ensemble resulted in a rapid and remarkable fluorescence off-on (emission at 565 nm). The practical use of an 'ensemble' was demonstrated by its application to the detection of iodide in the living cells.

Original language	English
Pages (from-to)	404-408
Number of pages	5
Journal	Sensors and Actuators B: Chemical
Volume	213
DOIs	https://doi.org/10.1016/j.snb.2015.02.117
State	Published - 5 Jul 2015

Keywords

Mercury Iodide Human Umbilical Vein Endothelial Cells (HUVEC)
Phenothiazine (PTH)

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10.1016/j.snb.2015.02.117

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abstract = "A phenothiazine-aminothiourea-based open chemosensor (P1) has been designed and synthesized, which exhibits high selectivity toward Hg2+ by forming a 1:1 complex. In its Hg2+ ensemble, it is reported as a highly sensitive and selective probe for the detection of iodide based on the displacement approach in aqueous solution. The addition of iodide to a solution of phenothiazine-aminothiourea-Hg2+ ensemble resulted in a rapid and remarkable fluorescence off-on (emission at 565 nm). The practical use of an 'ensemble' was demonstrated by its application to the detection of iodide in the living cells.",

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T1 - Phenothiazine-aminothiourea-Hg(II) ensemble-based fluorescence turn-on toward iodide in aqueous media and imaging application in live cells

AU - Yang, Wenge

AU - Yang, Shouhai

AU - Guo, Qirun

AU - Zhang, Tuan

AU - Wu, Keyi

AU - Hu, Yonghong

PY - 2015/7/5

Y1 - 2015/7/5

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AB - A phenothiazine-aminothiourea-based open chemosensor (P1) has been designed and synthesized, which exhibits high selectivity toward Hg2+ by forming a 1:1 complex. In its Hg2+ ensemble, it is reported as a highly sensitive and selective probe for the detection of iodide based on the displacement approach in aqueous solution. The addition of iodide to a solution of phenothiazine-aminothiourea-Hg2+ ensemble resulted in a rapid and remarkable fluorescence off-on (emission at 565 nm). The practical use of an 'ensemble' was demonstrated by its application to the detection of iodide in the living cells.

KW - Mercury Iodide Human Umbilical Vein Endothelial Cells (HUVEC)

KW - Phenothiazine (PTH)

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M3 - 文章

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ER -

Phenothiazine-aminothiourea-Hg(II) ensemble-based fluorescence turn-on toward iodide in aqueous media and imaging application in live cells

Abstract

Keywords

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